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Acetaminophen / aspirin / caffeine and Tremors: What Users Say

Brand names: Excedrin, Excedrin Migraine, Migraine Relief, Goody's Headache Powders, Excedrin Extra Strength, Pamprin Max Menstrual Pain Relief, Migraine Formula, Extra Pain Relief, Goody's Extra-Strength Headache Powders, Goody's Extra Strength, Bayer Migraine Formula, Arthriten, ConRx Pain Reliever, Genace, Anacin Advanced Headache Formula, Backaid Inflammatory Pain Formula, Arthriten Inflammatory Pain Formula, PainAid Extra-Strength Formula CVS Extra Strength Headache Relief Medique Pain-Off Vanquish …show all brand names

Tremors: mentioned by 8 users (2.1%)

Based on user experiences from 387 Acetaminophen / aspirin / caffeine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 7.2%
anxiety 4.9%
dizziness 3.1%
vomiting 2.8%
upset stomach 2.6%
increased heart rate 2.1%
tremors 2.1%
headaches 1.6%
lightheadedness 1.6%
stomach pain 1.3%

Reviews for Acetaminophen / aspirin / caffeine

Commonly mentioned side effects
  • RS1...
  • Taken for less than 1 month
  • June 14, 2017

For Migraine "I had a horrible experience with Excedrin Migraine. Shortly after taking it, my heart started racing super fast, I got extremely anxious, and my body started shaking. Like other people are saying, if you are sensitive to caffeine, do not take this medicine. It didn't take my migraine away either, so it's not worth it at all."

1 / 10
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13 Report
  • zoa...
  • Taken for 1 to 6 months
  • December 7, 2019

For Migraine "I got this medication from my doctor to treat weekly migraines. However, I found that this medication has only made my migraines more frequent! If I take it one day, it’ll return the next day. I never used to wake up with headaches, but now every morning is tainted with migraine. If I can catch my headache in time, it gets rid of the headache but introduces shakiness, dizziness, and stomach pain. If I wait too long to take the medication (i.e., wake up with a full-blown migraine), then it still causes these side effects, but combined with the headache, nausea, and dizziness of migraine, I feel 10x worse. Without my headache, side effects are bearable. With it, though, I really just want to blink out of existence. Take with caution or avoid altogether. My migraine days have increased 7-fold since taking this medication."

3 / 10
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7 Report
  • KLH...
  • Taken for less than 1 month
  • February 25, 2023

For Pain/Fever "I started taking Excedrin Extra Strength just every morning for pain. I ran out of my regular over-the-counter pain medicine. After taking this for 3 days in a row, I started having rapid heart rate and palpitations, lethargy, and the ringing in my ear got a lot worse. I already have tinnitus and vertigo along with Meniere's disease. I was nauseated, shaking, and dizzy. All these side effects made it hard to even sit up or do much of anything. Definitely a bad reaction. It did help with the everyday pain I have when I wake up, but not worth taking with the side effects. I believe it's a possible allergic reaction."

1 / 10
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2 Report
  • Kay...
  • Taken for 10 years or more
  • April 12, 2021

For Migraine "I started using Excedrin Migraine in my twenties for migraines. I'm now 62 and continue to use it. It's a miracle drug for me. I do get stomach upset from it, so I try to take it with food. I can't take it around bedtime because I could never sleep (caffeine is in it). I take one pill. I took 2 once, and the shakiness and anxiety were through the roof. I hope they never stop manufacturing this product."

10 / 10
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0 Report
  • lil...
  • Taken for 1 to 2 years
  • September 17, 2015

For Migraine "Miracle over-the-counter drugs for migraines. It makes me wonder why I haven't heard about this drug until I saw the commercial on TV, lol. Don't drink coffee with this though, it made me very shaky-to the point where my latte was visibly shaking in my grasp :("

10 / 10
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2 Report

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  • Nsa...
  • Taken for less than 1 month
  • January 6, 2021

For Migraine "This medication takes the pain away, but the last time I took it, I had terrible anxiety. I felt nauseous and shaky, and nothing would take the feeling away. I had to deal with it for a while, and it felt horrible. I usually take half of one pill, but last time I took a whole."

3 / 10
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0 Report
  • Anonymous
  • June 24, 2009

For Pain/Fever "Had a reaction to the caffeine in the product. Extremely shaky. Not to be used when sensitive to caffeine."

2 / 10
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10 Report
  • Anonymous
  • September 24, 2009

For Migraine "Makes me shaky and doesn't relieve pain."

3 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.