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Abatacept and Headaches: What Users Say

Brand names: Orencia

Headaches: mentioned by 4 users (5.4%)

Based on user experiences from 74 Abatacept reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 10.8%
tiredness 9.5%
nausea 8.1%
fatigue 6.8%
diarrhea 5.4%
dizziness 5.4%
headaches 5.4%
back pain 4.1%
mouth sores 4.1%
rash 4.1%

Reviews for Abatacept

Commonly mentioned side effects
  • Jay...
  • Taken for 1 to 6 months
  • January 7, 2021

For Rheumatoid Arthritis "I was on Enbrel for over 15 years for RA. Shortly after I started on it, I told my rheumatologist it was a miracle drug. I still had flares, but the severe pain I had felt every day was pretty much gone. Then, after so many years, the pain started returning. My current rheumatologist switched me to Humira. After a month, it seemed to be helping. But I was having nausea and a continuous headache with occasional dizziness. It was so bad I asked my rheumatologist to switch me to something else. She then put me on Orencia. I've been on it for 6 weeks, but the pain I had before going on Humira has returned. And I also have nasal congestion 24/7. I'll give the Orencia a few more weeks, until my next appointment with my rheumatologist, and if the pain and congestion aren't any better, I'll see what she wants to do. As a side note, I've also been taking methotrexate for 15 years."

4 / 10
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31 Report
  • RA ...
  • Taken for less than 1 month
  • April 11, 2015

For Rheumatoid Arthritis "Got an infusion of Orencia on a Tuesday for worsening RA symptoms. Wednesday, I had a severe headache that basically incapacitated me. Thursday morning, I woke up with the same headache, sensitivity to light and sound, and a stiff neck. I was unable to stand up without vomiting. An ED doctor did a lumbar puncture and told me I had viral meningitis. That experience has made me reluctant to try another biologic."

1 / 10
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65 Report
  • Rua...
  • May 10, 2021

For Rheumatoid Arthritis "My Vectra score came back at 55 (high disease activity), and it was time to figure out a new course of meds. Methotrexate injections didn't help with the pain and thinned my hair. Next up, biologics. Enbrel was a no-go due to the possibility of heart failure, and I was already experiencing high cardiac output. My first Orencia infusion was 2/11/2021. I experienced really bad headaches, lower blood pressure, and extreme fatigue. The headaches and lower blood pressure subsided a little. My rheumatologist and the IV nurse said to stay with it because it does take time. After the fourth infusion, I began experiencing head and facial tingling, causing my eye to freeze for a few seconds then stop. Tingling also in my left arm, dizziness, sore throat, and stuffy nose. My rheumatologist told me to stop the medication and offered Xeljanz. *long sigh* I really don't want to go on this medication tour and was really hoping Orencia would have worked. I heard so many good things from people who benefited from it. Let's see what's next."

4 / 10
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18 Report

Frequently asked questions

  • Min...
  • Taken for less than 1 month
  • September 19, 2021

For Psoriatic Arthritis "I have just had my second infusion of Orencia. The first go-around, I had a headache and fever and aches for that night and most of the next few days. After the second dose, I have severe aches and pains in all joints and muscles, and my skin hurts to touch it. Plus, I have a cold or something that just came on a day after the infusion. I am wondering if it is going to work for me or if I need to change. I was on Simponi Aria for a year and a half, and then it stopped working. My question is, are these symptoms considered bad, or something that I have to put up with and hope they go away and the Orencia starts working without these side effects?"

2 / 10
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7 Report

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