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Abatacept and Diarrhea: What Users Say

Brand names: Orencia

Diarrhea: mentioned by 4 users (5.4%)

Based on user experiences from 74 Abatacept reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

pain 10.8%
tiredness 9.5%
nausea 8.1%
fatigue 6.8%
diarrhea 5.4%
dizziness 5.4%
headaches 5.4%
back pain 4.1%
mouth sores 4.1%
rash 4.1%

Reviews for Abatacept

Showing 4 reviews tagged with "diarrhea". Clear filters to view all 74 reviews.
Commonly mentioned side effects
  • Ore...
  • Taken for 1 to 6 months
  • May 15, 2019

For Rheumatoid Arthritis "I am a 49-year-old male. I was diagnosed with RA in 1997. I was on Humira for 10 years, which helped greatly, but the side effects began showing, so I was forced to stop. I was off all RA meds for a couple of years, and my condition began deteriorating again. I went on Orencia IV drip. I began showing almost all of the side effects listed about a month after my first dose. It was slowly poisoning me. I was sick all the time and showing severe symptoms: exhaustion, night sweats, back pain, migraines for 8 days straight, diarrhea, nausea, and a level of discomfort I've never felt. It's an awful medicine with crippling side effects. It is important to note that the side effects were worse than the RA itself, and my condition is moderate to severe. My suggestion is to avoid this medication at all costs. I was put on an anti-nausea pill that is used for chemo patients. If you do some research, you will find that 25% of the people on Orencia have a bad experience."

1 / 10
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127 Report
  • Dai...
  • Taken for 6 months to 1 year
  • February 6, 2020

For Rheumatoid Arthritis "Worked great for 9 months. (moderate-severe with positive RA factor) Went off this for around three weeks due to a mix-up with co-pay. Now, two straight weeks of stomach rumbling and diarrhea. Probiotics, Pepto-Bismol, nothing is helping. This is the only RA med that has worked for me, so I really hope my doctor can get me over this. I am on a copay plan through an assistance fund, and they pay what Medicare/Anthem doesn't cover, $1500/month. Before Orencia, I was unable to function, so I'm very thankful because it gave me some of my life back."

7 / 10
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49 Report
  • mic...
  • Taken for 6 months to 1 year
  • September 3, 2021

For Rheumatoid Arthritis "I liked this drug although it didn't stop my wrist pain. I had weekly injections and besides some issues with fatigue and diarrhea, it was pretty good. I was taking it with Plaquenil as well. My rheumatologist has switched me to Rinvoq, so we will have to see. Rinvoq has poor reviews, so I am a little scared."

8 / 10
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8 Report

Frequently asked questions

  • Not...
  • Taken for 1 to 6 months
  • March 24, 2025

For Rheumatoid Arthritis "I started Orencia four weeks ago after Humira and Enbrel did nothing for me. I'm taking it with methotrexate. I get hit with nausea and diarrhea for like a day or two after my dose. I've had a flare for the past two months now, and I really need this stuff to start working."

5 / 10
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