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Trospium extended-release capsules

Pronunciation

Generic Name: trospium (TROSE-pee-um)
Brand Name: Sanctura XR

Trospium extended-release capsules are used for:

Treating overactive bladder with symptoms such as urinary incontinence, urgency, and frequency.

Trospium extended-release capsules are an antispasmodic and antimuscarinic agent. It works by reducing muscle tone of the bladder, which decreases urinary spasm and frequency.

Do NOT use trospium extended-release capsules if:

  • you are allergic to any ingredient in trospium extended-release capsules
  • you have delayed or slow emptying of the stomach or uncontrolled narrow-angle glaucoma, you are unable to urinate, or you are at risk of developing these conditions
  • you have severe kidney problems
  • you are taking a solid oral potassium product (eg, tablet). If you need to take a potassium supplement, discuss with your doctor the best way for you to take potassium while you are also taking trospium extended-release capsules.

Contact your doctor or health care provider right away if any of these apply to you.

Before using trospium extended-release capsules:

Some medical conditions may interact with trospium extended-release capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you use alcohol or have a history of alcohol abuse
  • if you have liver or kidney problems, or glaucoma or increased pressure in the eye
  • if you have stomach or bowel problems (eg, inflammation, constipation, blockage, problems with the muscles in your intestines), myasthenia gravis, bladder blockage, or trouble urinating

Some MEDICINES MAY INTERACT with trospium extended-release capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Solid oral potassium products (eg, tablets) because the risk of stomach or bowel irritation may be increased by trospium extended-release capsules
  • Anticholinergic medicines (eg, scopolamine), metformin, morphine, procainamide, tenofovir, or vancomycin because they may increase the risk of trospium extended-release capsules's side effects
  • Phenothiazines (eg, thioridazine) because their effectiveness may be decreased by trospium extended-release capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if trospium extended-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use trospium extended-release capsules:

Use trospium extended-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with trospium extended-release capsules. Talk to your pharmacist if you have questions about this information.
  • Take trospium extended-release capsules by mouth with water on an empty stomach at least 1 hour before eating, preferably in the morning or as directed by your doctor.
  • If you miss a dose of trospium extended-release capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use trospium extended-release capsules.

Important safety information:

  • Trospium extended-release capsules may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use trospium extended-release capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol within 2 hours before or after you take trospium extended-release capsules.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using trospium extended-release capsules; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Trospium extended-release capsules may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.
  • Tell your doctor or dentist that you take trospium extended-release capsules before you receive any medical or dental care, emergency care, or surgery.
  • A severe and sometimes life-threatening side effect called angioedema has been reported with trospium extended-release capsules. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.
  • Use trospium extended-release capsules with caution in the ELDERLY; they may be more sensitive to its effects, especially dry mouth, constipation, stomach pain or upset, and trouble urinating.
  • Trospium extended-release capsules should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking trospium extended-release capsules while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you take trospium extended-release capsules, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of trospium extended-release capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth or eyes; gas; nasal dryness; nausea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); chest pain; confusion; dark urine; difficulty urinating; fainting; fast or irregular heartbeat; hallucinations; mental or mood changes; muscle pain or weakness; red, swollen, peeling, or blistered skin; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fast or irregular heartbeat.

Proper storage of trospium extended-release capsules:

Store trospium extended-release capsules at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep trospium extended-release capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about trospium extended-release capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Trospium extended-release capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take trospium extended-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about trospium extended-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to trospium extended-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using trospium extended-release capsules.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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