Medically reviewed by Drugs.com. Last updated on Oct 10, 2020.
- Very bad and sometimes deadly infections have happened in patients who take Simponi Aria (golimumab). Most people who had these infections were taking other drugs to lower the immune system like methotrexate or steroid drugs. If you have any infection, are taking antibiotics now or in the recent past, or have had many infections, talk with your doctor.
- TB (tuberculosis) has been seen in patients started on Simponi Aria (golimumab). These patients were exposed to TB in the past, but never got the infection. You will be tested to see if you have been exposed to TB before starting Simponi Aria (golimumab).
- Lymphoma and other cancers have happened in people who take Simponi Aria (golimumab) or drugs like it. This has been deadly in some cases. Talk with the doctor.
Uses of Simponi Aria:
- It is used to treat some types of arthritis.
- It is used to treat ankylosing spondylitis.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Simponi Aria?
- If you are allergic to Simponi Aria (golimumab); any part of Simponi Aria (golimumab); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have an infection.
- If you are taking any of these drugs: Abatacept, adalimumab, anakinra, certolizumab, etanercept, infliximab, rituximab, or tocilizumab.
This is not a list of all drugs or health problems that interact with Simponi Aria (golimumab).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Simponi Aria (golimumab) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Simponi Aria?
- Tell all of your health care providers that you take Simponi Aria (golimumab). This includes your doctors, nurses, pharmacists, and dentists.
- If you have had hepatitis B before or carry the virus, Simponi Aria (golimumab) can cause the virus to become active. This can lead to very bad and sometimes deadly liver problems. You will be tested for hepatitis B before starting Simponi Aria (golimumab). You will need to watch for signs of hepatitis while taking Simponi Aria (golimumab) and for several months after stopping it. Talk with your doctor.
- Talk with your doctor before getting any vaccines. Use of some vaccines with Simponi Aria (golimumab) may either raise the chance of an infection or make the vaccine not work as well.
- Do not get a weakened bacteria like BCG for bladder cancer while you use Simponi Aria (golimumab). Talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have your skin checked. Tell your doctor if you have any skin changes like a new wart, skin sore or reddish bump that bleeds or does not heal, or a change in the color or size of a mole.
- Allergic reactions have happened with Simponi Aria (golimumab). Some reactions may be very bad or life-threatening. When allergic reactions have happened with infusions of Simponi Aria (golimumab), most of the time they have happened during the infusion or within 1 hour after the infusion. Call your doctor right away if you have any signs that are not normal.
- If you are 65 or older, use Simponi Aria (golimumab) with care. You could have more side effects.
- This medicine is not approved for use in children younger than 18 years of age. Talk with the doctor.
- If you used Simponi Aria (golimumab) when you were pregnant, tell your baby's doctor. Your baby may have a higher chance of getting an infection for at least 6 months after birth. Your baby's doctor will also need to decide when your baby is to get any vaccines. Certain vaccines may cause infections that can lead to very bad health problems or death if given within 6 months after birth.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Simponi Aria) best taken?
Use Simponi Aria (golimumab) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of lupus like a rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Chest pain or pressure.
- Feeling very tired or weak.
- Any unexplained bruising or bleeding.
- Pale skin.
- Red scaly patches or bumps that are pus filled.
- A skin lump or growth.
- Flu-like signs.
- Warm, red, or painful skin or sores on the body.
- Call your doctor right away if you have a swollen gland, night sweats, shortness of breath, or weight loss without trying.
- Heart failure has happened with Simponi Aria (golimumab), as well as heart failure that has gotten worse in people who already have it. Sometimes, this has been deadly. Tell your doctor if you have heart disease. Call your doctor right away if you have shortness of breath, a big weight gain, a heartbeat that is not normal, or swelling in the arms or legs that is new or worse.
- Rarely, people using drugs like this one have had nervous system problems. Sometimes, these problems have not gone away. Call your doctor right away if you have a burning, numbness, or tingling feeling that is not normal; change in eyesight; dizziness; seizures; or weakness in your arms or legs.
What are some other side effects of Simponi Aria?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Irritation where Simponi Aria (golimumab) is given.
- Signs of a common cold.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Simponi Aria?
- If you need to store Simponi Aria (golimumab) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Simponi Aria (golimumab) is refilled. If you have any questions about Simponi Aria (golimumab), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
More about Simponi Aria (golimumab)
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- Drug class: TNF alfa inhibitors
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