Generic Name: nateglinide (NA-te-GLYE-nide)
Brand Name: Starlix
Nateglinide is used for:
Lowering blood sugar levels in patients with type 2 diabetes. It used along with diet and exercise. It may also be used for other conditions as determined by your doctor.
Nateglinide is an antidiabetic agent. It works by causing insulin to be released from the pancreas. This helps to lower blood glucose levels.
Do NOT use nateglinide if:
- you are allergic to any ingredient in nateglinide
- you have type 1 diabetes
- you have a certain problem associated with diabetes (diabetic ketoacidosis)
Contact your doctor or health care provider right away if any of these apply to you.
Before using nateglinide:
Some medical conditions may interact with nateglinide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have adrenocortical, pituitary, liver, or kidney problems
- if you have a high fever, or poor health or nutrition
Some MEDICINES MAY INTERACT with nateglinide. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Amiodarone, beta-adrenergic blockers (eg, metoprolol), gemfibrozil, guanethidine, imidazoles (eg, ketoconazole), monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oxandrolone, or salicylates (eg, aspirin) because the risk of low blood sugar may be increased
- Corticosteroids (eg, prednisone), phenytoin, rifamycins (eg, rifampin), somatropin, St. John's wort, sympathomimetics (eg, pseudoephedrine), thiazides (eg, hydrochlorothiazide), or thyroid hormones (eg, levothyroxine) because they may decrease nateglinide's effectiveness
- Somatostatin analogs (eg, octreotide) because they may decrease nateglinide's effectiveness or increase the risk of low blood sugar
This may not be a complete list of all interactions that may occur. Ask your health care provider if nateglinide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use nateglinide:
Use nateglinide as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take nateglinide by mouth 1 to 30 minutes before meals.
- If you skip a meal, you must also skip your scheduled dose to avoid the risk of low blood sugar levels (hypoglycemia).
- Talk to your doctor or other health care provider about what to do if you miss a dose of nateglinide.
Ask your health care provider any questions you may have about how to use nateglinide.
Important safety information:
- Nateglinide may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use nateglinide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Follow the diet and exercise program given to you by your health care provider.
- Strenuous exercise, drinking alcohol, fever, infection, surgery, trauma, dieting, and skipping meals can affect your blood sugar levels.
- Carry an ID card at all times that says you have diabetes.
- Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take nateglinide exactly as prescribed, tell your doctor.
- Nateglinide may cause low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you more hungry. It is a good idea to carry a reliable source of glucose (eg, tablets or gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.
- Tell your doctor or dentist that you take nateglinide before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including fasting blood sugar levels and hemoglobin A1c levels, may be performed while you use nateglinide. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use nateglinide with caution in the ELDERLY; they may be more sensitive to its effects.
- Nateglinide should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use nateglinide if you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking nateglinide.
Possible side effects of nateglinide:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; flu-like symptoms (fever, chills, sore throat); joint pain; upper respiratory tract infection.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, stomach pain, unusual nausea or tiredness, yellowing of the skin or eyes); symptoms of low blood sugar (eg, anxiety, chills, fast heartbeat, headache, increased hunger, severe or persistent dizziness or drowsiness, tremors, unusual sweating, vision changes, weakness).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include changes in vision; headache; increased hunger; loss of consciousness; nervousness; seizures; shakiness; sweating; tiredness.Proper storage of nateglinide:
Store nateglinide at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store in a tightly closed container. Store away from heat, light, and moisture. Do not store in the bathroom. Keep nateglinide out of the reach of children and away from pets.
- If you have any questions about nateglinide, please talk with your doctor, pharmacist, or other health care provider.
- Nateglinide is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take nateglinide or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about nateglinide. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to nateglinide. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using nateglinide.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: meglitinides
Other brands: Starlix