What are Meglitinides?
Meglinitides work by stimulating the pancreas to release insulin in response to a meal. It closes ATP-dependent potassium channels in functioning pancreatic beta cells. This blockade of potassium channels depolarizes the beta cells, which leads to opening of calcium channels resulting in influx of calcium. Increased intracellular calcium induces insulin secretion.
Meglitinides are used in the treatment of Type 2 diabetes.
List of Meglitinides:
|Drug Name||Avg. Rating||Reviews|
Generic name: repaglinide
Generic name: nateglinide
|For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).|
Medical conditions associated with meglitinides:
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