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Generic Name: Ticagrelor (tye KA grel or)
Brand Name: Brilinta

Medically reviewed by Last updated on Oct 3, 2019.


  • This medicine may cause very bad and sometimes deadly bleeding. Do not use if you are having any bleeding problems (including bleeding ulcer) or if you have ever had bleeding in the brain. Do not stop taking Brilinta (ticagrelor) without talking to your doctor. Stopping Brilinta (ticagrelor) when you are not supposed to may raise the chance of heart attack, stroke, and death. Use as you have been told.
  • Tell all of your health care providers that you take Brilinta (ticagrelor). This includes your doctors, nurses, pharmacists, and dentists. This medicine may need to be stopped before certain types of surgery as your doctor has told you. If Brilinta (ticagrelor) is stopped, your doctor will tell you when to start taking Brilinta (ticagrelor) again after your surgery or procedure.
  • Do not take more than 100 mg a day of aspirin when taking Brilinta (ticagrelor). This medicine may not work as well. Talk with your doctor.

Uses of Brilinta:

  • It is used to lower the chance of heart attack, stroke, and death in some people.
  • It is used to lower the chance of blockage of a stent after a stent is placed in the heart.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Brilinta?

  • If you have an allergy to ticagrelor or any other part of Brilinta (ticagrelor)
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with Brilinta (ticagrelor), like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with Brilinta (ticagrelor).
  • If you have liver disease.
  • If you are breast-feeding. Do not breast-feed while you take Brilinta (ticagrelor).

This is not a list of all drugs or health problems that interact with Brilinta (ticagrelor).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Brilinta (ticagrelor) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Brilinta?

  • Tell all of your health care providers that you take Brilinta (ticagrelor). This includes your doctors, nurses, pharmacists, and dentists.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • If you fall or hurt yourself, or if you hit your head, call your doctor right away. Talk with your doctor even if you feel fine.
  • Some drugs may look the same as Brilinta (ticagrelor) or may have names that sound like Brilinta (ticagrelor). Always check to make sure you have the right product. If you see any change in the way Brilinta (ticagrelor) looks like shape, color, size, or wording, check with your pharmacist.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Brilinta (ticagrelor) while you are pregnant.

How is this medicine (Brilinta) best taken?

Use Brilinta (ticagrelor) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take Brilinta (ticagrelor) at the same time of day.
  • Take with or without food.
  • If you cannot swallow the tablet whole, the tablet can be crushed and mixed with water. Drink right away after mixing. Refill the glass with water, stir, and drink.
  • Those who have feeding tubes may use the tablet. Crush the tablet and mix it with water. Flush the feeding tube after Brilinta (ticagrelor) is given.
  • To gain the most benefit, do not miss doses.
  • Keep taking Brilinta (ticagrelor) as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Very bad headache.
  • Shortness of breath.
  • Slow heartbeat.
  • A heartbeat that does not feel normal.

What are some other side effects of Brilinta?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Brilinta?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Brilinta (ticagrelor) is refilled. If you have any questions about Brilinta (ticagrelor), please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.