They both contain the same active ingredient but each is approved for a slightly different purpose so has a different criteria for use.
Olux - is approved for short‐term topical treatment of inflammatory and
pruritic manifestations of corticosteroid‐responsive dermatoses of the
scalp and short term treatment of mild to moderate plaque‐type
psoriasis on non‐scalp regions
Olux‐E - is approved for short‐term topical treatment of inflammatory and
pruritic manifestations of corticosteroid‐responsive dermatoses.
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