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Medications for Breast Cancer, Metastatic

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Ibrance 6.9 73 reviews for Ibrance to treat Breast Cancer, Metastatic
Rx N
Generic name:
palbociclib systemic
Drug class:
CDK 4/6 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
letrozole 7.2 27 reviews for letrozole to treat Breast Cancer, Metastatic
Rx D N
Generic name:
letrozole systemic
Brand name:
Femara
Drug class:
hormones/antineoplastics, aromatase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
anastrozole 6.4 12 reviews for anastrozole to treat Breast Cancer, Metastatic
Rx D N
Generic name:
anastrozole systemic
Brand name:
Arimidex
Drug class:
hormones/antineoplastics, aromatase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Femara 7.0 8 reviews for Femara to treat Breast Cancer, Metastatic
Rx D N
Generic name:
letrozole systemic
Drug class:
hormones/antineoplastics, aromatase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Faslodex 6.3 33 reviews for Faslodex to treat Breast Cancer, Metastatic
Rx D N
Generic name:
fulvestrant systemic
Drug class:
hormones/antineoplastics, estrogen receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Xeloda 4.5 14 reviews for Xeloda to treat Breast Cancer, Metastatic
Rx D N
Generic name:
capecitabine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Kisqali 8.5 23 reviews for Kisqali to treat Breast Cancer, Metastatic
Rx N
Generic name:
ribociclib systemic
Drug class:
CDK 4/6 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
palbociclib 7.0 86 reviews for palbociclib to treat Breast Cancer, Metastatic
Rx N
Generic name:
palbociclib systemic
Brand name:
Ibrance
Drug class:
CDK 4/6 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Herceptin 10 2 reviews for Herceptin to treat Breast Cancer, Metastatic
Rx D N
Generic name:
trastuzumab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
tamoxifen 3.0 2 reviews for tamoxifen to treat Breast Cancer, Metastatic
Rx D N
Generic name:
tamoxifen systemic
Brand name:
Soltamox
Drug class:
hormones/antineoplastics, selective estrogen receptor modulators
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
ribociclib 8.5 25 reviews for ribociclib to treat Breast Cancer, Metastatic
Rx N
Generic name:
ribociclib systemic
Brand name:
Kisqali
Drug class:
CDK 4/6 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Arimidex 6.2 5 reviews for Arimidex to treat Breast Cancer, Metastatic
Rx D N
Generic name:
anastrozole systemic
Drug class:
hormones/antineoplastics, aromatase inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Enhertu 7.7 13 reviews for Enhertu to treat Breast Cancer, Metastatic
Rx N
Generic name:
fam-trastuzumab deruxtecan systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
capecitabine 5.7 24 reviews for capecitabine to treat Breast Cancer, Metastatic
Rx D N
Generic name:
capecitabine systemic
Brand name:
Xeloda
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
fam-trastuzumab deruxtecan 7.3 14 reviews for fam-trastuzumab deruxtecan to treat Breast Cancer, Metastatic
Rx N
Generic name:
fam-trastuzumab deruxtecan systemic
Brand name:
Enhertu
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
fulvestrant 6.3 47 reviews for fulvestrant to treat Breast Cancer, Metastatic
Rx D N
Generic name:
fulvestrant systemic
Brand name:
Faslodex
Drug class:
hormones/antineoplastics, estrogen receptor antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Taxotere 9.0 1 review for Taxotere to treat Breast Cancer, Metastatic
Rx D N
Generic name:
docetaxel systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tykerb Rate Add review
Rx D N
Generic name:
lapatinib systemic
Drug class:
EGFR inhibitors, HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Halaven 9.4 8 reviews for Halaven to treat Breast Cancer, Metastatic
Rx D N
Generic name:
eribulin systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Abraxane 0.0 1 review for Abraxane to treat Breast Cancer, Metastatic
Rx D N
Generic name:
paclitaxel protein-bound systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
Perjeta Rate Add review
Rx D N
Generic name:
pertuzumab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
trastuzumab 10 2 reviews for trastuzumab to treat Breast Cancer, Metastatic
Rx D N
Generic name:
trastuzumab systemic
Brand names:
Herceptin, Herzuma, Ogivri, Kanjinti, Ontruzant, Trazimera
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Gemzar 7.0 1 review for Gemzar to treat Breast Cancer, Metastatic
Rx D N
Generic name:
gemcitabine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
eribulin 8.7 10 reviews for eribulin to treat Breast Cancer, Metastatic
Rx D N
Generic name:
eribulin systemic
Brand name:
Halaven
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
docetaxel 5.0 2 reviews for docetaxel to treat Breast Cancer, Metastatic
Rx D N
Generic name:
docetaxel systemic
Brand name:
Taxotere
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
paclitaxel 8.3 3 reviews for paclitaxel to treat Breast Cancer, Metastatic
Rx D N
Generic name:
paclitaxel systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
pertuzumab Rate Add review
Rx D N
Generic name:
pertuzumab systemic
Brand name:
Perjeta
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Soltamox Rate Add review
Rx D N
Generic name:
tamoxifen systemic
Drug class:
hormones/antineoplastics, selective estrogen receptor modulators
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ixempra Rate Add review
Rx D N
Generic name:
ixabepilone systemic
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Lynparza 7.3 4 reviews for Lynparza to treat Breast Cancer, Metastatic
Rx D N
Generic name:
olaparib systemic
Drug class:
PARP inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
gemcitabine 7.0 1 review for gemcitabine to treat Breast Cancer, Metastatic
Rx D N
Generic name:
gemcitabine systemic
Brand names:
Gemzar, Infugem
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Kadcyla Rate Add review
Rx D N
Generic name:
ado-trastuzumab emtansine systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
lapatinib Rate Add review
Rx D N
Generic name:
lapatinib systemic
Brand name:
Tykerb
Drug class:
EGFR inhibitors, HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Fareston Rate Add review
Rx D N
Generic name:
toremifene systemic
Drug class:
hormones/antineoplastics, selective estrogen receptor modulators
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ado-trastuzumab emtansine Rate Add review
Rx D N
Generic name:
ado-trastuzumab emtansine systemic
Brand name:
Kadcyla
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
bevacizumab Off-label 9.0 3 reviews for bevacizumab to treat Breast Cancer, Metastatic
Rx C N
Generic name:
bevacizumab systemic
Drug class:
VEGF/VEGFR inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Off-label:
Yes
olaparib 7.3 5 reviews for olaparib to treat Breast Cancer, Metastatic
Rx D N
Generic name:
olaparib systemic
Brand name:
Lynparza
Drug class:
PARP inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
paclitaxel protein-bound 0.0 1 review for paclitaxel protein-bound to treat Breast Cancer, Metastatic
Rx D N
Generic name:
paclitaxel protein-bound systemic
Brand name:
Abraxane
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
toremifene Rate Add review
Rx D N
Generic name:
toremifene systemic
Brand name:
Fareston
Drug class:
hormones/antineoplastics, selective estrogen receptor modulators
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Herzuma Rate Add review
Rx D N
Generic name:
trastuzumab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ixabepilone Rate Add review
Rx D N
Generic name:
ixabepilone systemic
Brand name:
Ixempra
Drug class:
mitotic inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Ogivri Rate Add review
Rx D N
Generic name:
trastuzumab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Infugem Rate Add review
Rx D N
Generic name:
gemcitabine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
Kanjinti Rate Add review
Rx D N
Generic name:
trastuzumab systemic
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
margetuximab Rate Add review
Rx N
Generic name:
margetuximab systemic
Brand name:
Margenza
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Ontruzant Rate Add review
Rx D N
Generic name:
trastuzumab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Trazimera Rate Add review
Rx D N
Generic name:
trastuzumab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Margenza Rate Add review
Rx N
Generic name:
margetuximab systemic
Drug class:
HER2 inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

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