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Generic Name: fulvestrant (ful VES trant)
Brand Names: Faslodex

What is Faslodex?

Faslodex (fulvestrant) is an anti-estrogen medication. It works by blocking the actions of estrogen in the body. Certain types of breast cancer use estrogen to grow and multiply in the body.

Faslodex is used to treat some hormone-related breast cancer.

Faslodex is also used in postmenopausal women whose breast cancer has progressed after treatment with other anti-estrogen medication.

Important information

You should not receive Faslodex if you are pregnant.

Before you receive Faslodex, tell your doctor if you have liver disease, a bleeding or blood-clotting disorder, or thrombocytopenia (a low level of platelets in the blood). Also tell your doctor if you are taking a blood thinner such as warfarin (Coumadin, Jantoven).

Call your doctor for instructions if you miss an appointment for your injection.

Before taking this medicine

You should not receive Faslodex if you are allergic to fulvestrant, or if you are pregnant.

To make sure Faslodex is safe for you, tell your doctor if you have:

  • liver disease;

  • a bleeding or blood clotting disorder; or

  • thrombocytopenia (a low level of platelets in the blood).

Do not use Faslodex if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy during treatment.

It is not known whether fulvestrant passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Faslodex.

How is Faslodex given?

Faslodex is injected into a muscle of your buttock. Your doctor, nurse, or other healthcare provider will give you this injection.

Faslodex is usually given once every 2 weeks at first, and then once a month. Do not miss any scheduled appointments.

Faslodex dosing information

Usual Adult Dose for Breast Cancer:

Initial dose: 500 mg IM on days 1, 15, and 29, then once a month thereafter.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Faslodex injection.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving Faslodex?

Fulvestrant can pass into body fluids (urine, feces, vomit). For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

Faslodex side effects

Get emergency medical help if you have signs of an allergic reaction to Faslodex: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common Faslodex side effects may include:

  • headache;

  • bone pain, joint pain, muscle pain;

  • nausea, vomiting, loss of appetite, constipation;

  • weakness, feeling tired;

  • cough, trouble breathing;

  • abnormal liver function tests;

  • hot flashes; or

  • pain where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Faslodex?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • a blood thinner - warfarin, Coumadin, Jantoven.

This list is not complete. Other drugs may interact with fulvestrant, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about Faslodex.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Faslodex only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 6.01. Revision Date: 2015-08-05, 7:46:18 AM.