Mitotic inhibitors
A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Mitotic inhibitors are drugs derived from natural plant sources. They inhibit cell division or mitosis, where a single cell divides into two genetically identical daughter cells. Mitotic inhibitors bind to tubulin and inhibit its polymerization into microtubules. Microtubules are structures responsible for pulling the cell apart when it divides. Mitotic inhibitors affect cancer cells more than normal cells because cancer cells divide (mitotic cell division) more rapidly therefore are more susceptible to mitotic inhibition.
Different mitotic inhibitors are used to treat particular types of cancers, such as leukemia, lymphoma, breast cancer, lung cancer and other types of cancers.
See also
Medical conditions associated with mitotic inhibitors:
- Acute Lymphoblastic Leukemia
- Acute Lymphocytic Leukemia
- Acute Myeloid Leukemia
- Anaplastic Oligodendroglioma
- Breast Cancer
- Breast Cancer, Adjuvant
- Breast Cancer, Metastatic
- Cancer
- Choriocarcinoma
- Evan's Syndrome
- Gastric Cancer
- Head and Neck Cancer
- Histiocytosis
- Hodgkin's Lymphoma
- Kaposi's Sarcoma
- Lymphoma
- Multiple Myeloma
- Mycosis Fungoides
- Neuroblastoma
- Non-Hodgkin's Lymphoma
- Non-Small Cell Lung Cancer
- Ovarian Cancer
- Prostate Cancer
- Rhabdomyosarcoma
- Small Cell Lung Cancer
- Solid Tumors
- Testicular Cancer
- Wilms' Tumor
