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Zonatuss Side Effects

Generic name: benzonatate

Medically reviewed by Last updated on Mar 5, 2024.

Note: This document contains side effect information about benzonatate. Some dosage forms listed on this page may not apply to the brand name Zonatuss.

Applies to benzonatate: oral capsule, oral capsule liquid filled.

Serious side effects of Zonatuss

Along with its needed effects, benzonatate (the active ingredient contained in Zonatuss) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking benzonatate:


Get emergency help immediately if any of the following symptoms of overdose occur while taking benzonatate:

Symptoms of overdose

Other side effects of Zonatuss

Some side effects of benzonatate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

For Healthcare Professionals

Applies to benzonatate: oral capsule.


The most serious side effects reported were bronchospasm, laryngospasm, and cardiovascular collapse.[Ref]


Frequency not reported: Bronchospasm, laryngospasm, cardiovascular collapse, hypersensitivity[Ref]

Nervous system

Frequency not reported: Sedation, headache, dizziness, mental confusion, visual hallucinations.[Ref]


Frequency not reported: Nasal congestion, numbness of the chest[Ref]


Frequency not reported: Constipation, nausea, GI upset[Ref]


Frequency not reported: Pruritus, skin eruptions[Ref]


Frequency not reported: Sensation of burning in the eyes[Ref]


Frequency not reported: Vague "chilly" sensation[Ref]

Frequently asked questions


1. (2001) "Product Information. Tessalon (benzonatate)." Forest Pharmaceuticals

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.