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Trimethadione Side Effects

Applies to trimethadione: oral capsule, oral tablet chewable

Dermatologic

Frequency not reported: Acneiform or morbilliform skin rash that may progress to exfoliative dermatitis or to severe forms of erythema multiforme, lupus erythematosus and lymphadenopathies simulating malignant lymphoma, pruritus (associated with lymphadenopathy and hepatosplenomegaly)[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting, abdominal pain, gastric distress, bleeding gums[Ref]

Genitourinary

Frequency not reported: Vaginal bleeding, albuminuria[Ref]

Hematologic

Frequency not reported: Neutropenia, leukopenia, eosinophilia, thrombocytopenia, pancytopenia, agranulocytosis, hypoplastic anemia, fatal aplastic anemia[Ref]

Hepatic

Rare (less than 0.1%): Hepatitis[Ref]

Musculoskeletal

Frequency not reported: Myasthenia gravis-like syndrome[Ref]

Nervous system

Frequency not reported: Drowsiness, fatigue, malaise, insomnia, vertigo, headache, paresthesias, precipitation of grand mal seizures, increased irritability[Ref]

Ocular

Frequency not reported: Hemeralopia, photophobia, diplopia, retinal and petechial hemorrhages[Ref]

Other

Frequency not reported: Hiccups, anorexia, weight loss, hair loss, changes in blood pressure, albuminuria[Ref]

Psychiatric

Frequency not reported: Personality changes[Ref]

Respiratory

Frequency not reported: Epistaxis[Ref]

References

1. "Product Information. Tridione (trimethadione)" Abbott Pharmaceutical, Abbott Part, IL.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.