TriCor Side Effects
Generic Name: fenofibrate
Medically reviewed by Drugs.com. Last updated on Aug 12, 2020.
Note: This document contains side effect information about fenofibrate. Some of the dosage forms listed on this page may not apply to the brand name TriCor.
Common side effects of TriCor include: increased serum aspartate aminotransferase and increased serum alanine aminotransferase. Other side effects include: abnormal hepatic function tests, increased creatine phosphokinase in blood specimen, and increased serum transaminases. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to fenofibrate: oral capsule, oral tablet
Side effects requiring immediate medical attention
Along with its needed effects, fenofibrate (the active ingredient contained in TriCor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking fenofibrate:
- Chronic indigestion
- dark urine
- muscle cramps, spasms, stiffness, swelling, or weakness
- troubled breathing
- unusual bleeding or bruising
- unusual tiredness or weakness
- yellow eyes or skin
Incidence not known
- bloody urine
- decreased frequency or amount of urine
- difficulty in moving
- fast heartbeat
- general tiredness and weakness
- increased blood pressure
- increased thirst
- joint pain or swelling
- light-colored stools
- loss of appetite
- lower back or side pain
- pains in the stomach, side, or abdomen, possibly radiating to the back
- pale skin
- swelling of the face, fingers, or lower legs
- troubled breathing with exertion
- upper right abdominal or stomach pain
- weight gain
Side effects not requiring immediate medical attention
Some side effects of fenofibrate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Runny nose
- stuffy nose
Incidence not known
- Lack or loss of strength
For Healthcare Professionals
Applies to fenofibrate: oral capsule, oral tablet
Common (1% to 10%): Liver function tests abnormal, AST increased, ALT increased
Uncommon (0.1% to 1%): Cholelithiasis
Rare (less than 0.1%): Hepatitis
During clinical trials, transaminase increases to greater than 3 times the upper limit of normal (3 x ULN) occurred in 5.3% of patients taking fenofibrate compared with 1.1% of those on placebo; the incidence of increased transaminases appeared to be dose-related.[Ref]
Very common (10% or more): Rhinitis (up to 23.2%), bronchitis (16.4%)
Common (1% to 10%): Respiratory disorder, pharyngitis, sinusitis
Uncommon (0.1% to 1%): Pulmonary embolism
Very rare (less than 0.01%): Interstitial pneumopathy
Postmarketing reports: Interstitial lung disease[Ref]
Very common (10% or more): Arthralgia (up to 25.1%), back pain (up to 15%)
Common (1% to 10%): Back pain, myalgia
Uncommon (0.1% to 1%): Diffuse myalgia, myositis, muscle cramp, muscle weakness
Very rare (less than 0.01%): Rhabdomyolysis
Frequency not reported: Arthritis, tenosynovitis, joint disorder, arthrosis, leg cramp, bursitis, myasthenia
Postmarketing reports: Muscle spasm[Ref]
Very common (10% or more): Abdominal pain (up to 15.9%)
Common (1% to 10%): Nausea, constipation, diarrhea, vomiting, flatulence
Uncommon (0.1% to 1%): Pancreatitis
Frequency not reported: Dyspepsia, gastroenteritis, rectal disorder, esophagitis, gastritis, colitis, tooth disorder, gastrointestinal disorder, duodenal ulcer, peptic ulcer, rectal hemorrhage, eructation, gamma glutamyl transpeptidase, dry mouth[Ref]
Rare (less than 0.1%): Peripheral neuropathy
Uncommon (0.1% to 1%): Photosensitivity reaction
Rare (0.01% to 0.1%): Alopecia
Very rare (less than 0.01%): Cutaneous photosensitivity with erythema, vesiculation, nodulation
Frequency not reported: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, acne, sweating, fungal dermatitis, skin disorder, contact dermatitis, maculopapular rash, nail disorder, skin ulcer
Postmarketing reports: Ecchymosis[Ref]
Uncommon (0.1% to 1%): Deep vein thrombosis
Frequency not reported: Angina pectoris, hypertension, vasodilatation, coronary artery disorder, electrocardiogram abnormal, extrasystole, myocardial infarct, peripheral vascular disorder, varicose vein, cardiovascular disorder, hypotension, palpitation, arrhythmia, phlebitis, tachycardia, atrial fibrillation[Ref]
Common (1% to 10%): Conjunctivitis
Very common (10% or more): Accidental injury (up to 18.4%), flu syndrome (up to 17.9%), chest pain (up to 10.1%)
Common (1% to 10%): Creatine phosphokinase increased, malaise, vertigo, fatigue
Uncommon (0.1% to 1%): Serum creatinine increased, urea increased
Rare (less than 0.1%): Sexual asthenia
Postmarketing reports: Asthenia[Ref]
Uncommon (0.1% to 1%): Sexual dysfunction
Rare (less than 0.1%): Hemoglobin decreased, leukopenia
Postmarketing reports: Hematocrit decreased[Ref]
Postmarketing reports: High-density lipoprotein cholesterol levels severely depressed[Ref]
Frequency not reported: Kidney function abnormal, urolithiasis
Postmarketing reports: Renal failure, acute renal failure[Ref]
Common (1% to 10%): Insomnia
Frequency not reported: Diabetes mellitus[Ref]
Rare (less than 0.1%): Hypersensitivity reaction
Frequency not reported: Allergic reaction[Ref]
1. Cerner Multum, Inc. "Australian Product Information." O 0
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. "Product Information. Tricor (fenofibrate)." Abbott Pharmaceutical, Abbott Park, IL.
4. "Product Information. Lofibra (fenofibrate)." Teva Pharmaceuticals (formerly Gate Pharmaceuticals), Sellersville, PA.
5. "Product Information. Fenoglide (fenofibrate)." Santarus Inc, San Diego, CA.
6. "Product Information. Fenofibrate (fenofibrate)." Mylan Pharmaceuticals Inc, Morgantown, WV.
7. "Product Information. Triglide (fenofibrate)." Sciele Pharma Inc, Atlanta, GA.
8. "Product Information. Antara (fenofibrate)." Lupin Pharmaceuticals Inc, Baltimore, MD.
9. "Product Information. Lipofen (fenofibrate)." Kowa Pharmaceuticals America (formerly ProEthic), Montgomery, AL.
More about TriCor (fenofibrate)
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- 15 Reviews
- Generic Availability
- Drug class: fibric acid derivatives
- FDA Approval History
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.