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Fibric acid derivatives

Other names: Fibrates

What are Fibric acid derivatives?

Fibric acid derivatives or fibrates are regarded as broad-spectrum lipid lowering drugs. Their main action is to decrease triglyceride levels but they also tend to reduce low density lipoprotein (LDL) cholesterol levels and help to raise high density lipoprotein (HDL) cholesterol. Fibrates appear to activate a protein called peroxisome proliferator-activated receptor alpha (PPAR-alpha). PPAR-alpha activates the enzyme lipoprotein lipase and ultimately results in decreased formation of very low-density lipoprotein (VLDL) cholesterol (which is converted into LDL cholesterol) and triglycerides and an increase in HDL cholesterol.

List of Fibric acid derivatives

View by  Generic | Brand
Drug Name Avg. Rating Reviews
fenofibrate systemic (Pro)
Brand names: Antara, Fenoglide, Lipofen, TriCor, Triglide
5.7
68 reviews
gemfibrozil systemic (Pro)
Brand name: Lopid
6.2
26 reviews
fenofibric acid systemic (Pro)
Brand names: Fibricor, Trilipix
5.1
25 reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.