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Lopid

Generic Name: gemfibrozil (jem FYE broe zil)
Brand Name: Lopid

Medically reviewed on September 25, 2017

What is Lopid?

Lopid helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

Lopid is used together with diet to treat very high cholesterol and triglyceride levels in people with pancreatitis.

Lopid is also used to lower the risk of stroke, heart attack, or other heart complications in certain people with high cholesterol and triglycerides who have not been helped by other treatment methods.

Lopid may also be used for purposes not listed in this medication guide.

Important Information

You should not take Lopid if you have severe liver or kidney disease, gallbladder disease, or if you are also taking repaglinide (Prandin), dasabuvir (Viekira Pak), or simvastatin (Zocor, Vytorin, Juvisync, Simcor).

Before taking this medicine

You should not use Lopid if you are allergic to it, if you have:

  • severe liver disease;

  • severe kidney disease;

  • gallbladder disease; or

  • if you are also taking repaglinide (Prandin), dasabuvir (Viekira Pak), or simvastatin (Zocor, Vytorin, Juvisync, Simcor).

To make sure Lopid is safe for you, tell your doctor if you have ever had:

It is not known whether Lopid will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether gemfibrozil passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking gemfibrozil.

How should I take Lopid?

Lopid is usually taken twice daily, 30 minutes before breakfast and dinner.

Follow all directions on your prescription label. Do not take Lopid in larger or smaller amounts or for longer than recommended.

Lopid is only part of a treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

While using Lopid, you may need frequent blood tests to check your liver function. Your kidney function may also need to be tested.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Lopid?

Avoid eating foods that are high in fat or cholesterol. Lopid will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It may interfere with your treatment.

Lopid side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, Lopid can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Also call your doctor at once if you have:

  • sharp pain in your upper stomach (especially after eating);

  • jaundice (yellowing of your skin or eyes);

  • pain or burning when you urinate;

  • blurred vision, eye pain, or seeing halos around lights; or

  • pale skin, easy bruising, unusual bleeding, feeling light-headed or short of breath, rapid heart rate, purple or red pinpoint spots under your skin.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Lopid?

Tell your doctor about all other medicines you use. Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them:

Many drugs can interact with Lopid, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine. Give a list of all your medicines to any healthcare provider who treats you.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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