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TriCor

Generic name: fenofibrateFEN-oh-FYE-brate ]
Drug class: Fibric acid derivatives

Medically reviewed by Philip Thornton, DipPharm. Last updated on Aug 20, 2023.

What is TriCor?

TriCor belongs to a group of drugs known as "fibrates." It helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

TriCor is used along with a proper diet to help to treat high cholesterol and high triglyceride levels.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help TriCor work better include exercising, losing weight if overweight, and stopping smoking.

Warnings

You should not take TriCor if you have liver disease, gallbladder disease, severe kidney disease, or if you are breast-feeding a baby.

Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

Before taking this medicine

You should not take TriCor if you are allergic to fenofibrate, or if you have:

Do not breast-feed while using this medicine, and for at least 5 days after your last dose.

To make sure TriCor is safe for you, tell your doctor if you have ever had:

Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease, diabetes, or poorly controlled hypothyroidism (underactive thyroid).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

TriCor is not approved for use by anyone younger than 18 years old.

How should I take TriCor?

Take TriCor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

TriCor may be taken with or without food. Follow the directions on your medicine label.

Swallow the tablet or capsule whole and do not crush, chew, dissolve, or open it.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if TriCor is effective.

TriCor is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Dosing information

Usual Adult Dose of TriCor for Hyperlipoproteinemia Type IIa (Elevated LDL):
145 mg orally once a day.

Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL):
145 mg orally once a day.

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL):
48 to 145 mg orally once a day.

Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL):
48 to 145 mg orally once a day.

Usual Geriatric Dose of TriCor for Hyperlipoproteinemia:
48 mg orally once a day. Increases in dosage should occur only after evaluating the effects on renal function and lipid levels at this dose, with a maximum recommended dose of 145 mg/24 hours.

atorvastatin, rosuvastatin, simvastatin, Lipitor, fenofibrate, Crestor, Vascepa, gemfibrozil, niacin, Lovaza

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What to avoid

Avoid eating foods high in fat or cholesterol, or TriCor will not be as effective.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

TriCor side effects

Get emergency medical help if you have signs of an allergic reaction to TriCor (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

In rare cases, fenofibrate can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.

Also call your doctor at once if you have:

Common TriCor side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect TriCor?

Some medicines can make TriCor much less effective when taken at the same time. If you take any of the following medicines, take your dose 1 hour before or 4 to 6 hours after you take the other medicine.

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may interact with fenofibrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Does TriCor interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use TriCor only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.