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Strattera Side Effects

Generic Name: atomoxetine

Note: This page contains side effects data for the generic drug atomoxetine. It is possible that some of the dosage forms included below may not apply to the brand name Strattera.

In Summary

Common side effects of Strattera include: insomnia, constipation, decreased appetite, and xerostomia. Other side effects include: erectile dysfunction, dysmenorrhea, dermatitis, urinary hesitancy, ejaculatory disorder, dizziness, dyspepsia, ejaculation failure, and diaphoresis. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to atomoxetine: oral capsule

As well as its needed effects, atomoxetine (the active ingredient contained in Strattera) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking atomoxetine, check with your doctor immediately:

Less common:
  • Hives or welts
  • irregular heartbeat
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • redness of the skin
  • skin rash
  • Painful, prolonged erection of your penis
Incidence not known:
  • Convulsions
  • dark colored urine
  • fainting
  • flu-like symptoms
  • loss of bladder control
  • muscle spasm or jerking of all extremities
  • pelvic pain in male
  • right upper belly pain or tenderness
  • sudden loss of consciousness
  • yellow eyes or skin

Minor Side Effects

Some atomoxetine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Acid or sour stomach
  • belching
  • bleeding between periods
  • change in amount of bleeding during periods
  • change in pattern of monthly periods
  • cough
  • decrease in the frequency of urination
  • decrease in urine amount
  • decreased appetite
  • decreased interest in sexual intercourse
  • difficulty having a bowel movement (stool)
  • difficulty in passing urine (dribbling)
  • dizziness
  • dry mouth
  • fever
  • headache
  • heartburn
  • heavy bleeding
  • inability to have or keep an erection
  • indigestion
  • irritability
  • loss in sexual ability, desire, drive, or performance
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • painful urination
  • shortness of breath
  • sleepiness or unusual drowsiness
  • stomach discomfort, upset, cramps, or pain
  • stuffy or runny nose
  • tightness of the chest
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
  • unusual stopping of menstrual bleeding
  • unusual tiredness or weakness
  • vomiting
Less common:
  • Abnormal dreams
  • abnormal orgasm
  • back pain
  • blistering, crusting, irritation, itching, or reddening of the skin
  • bloated or full feeling
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in hearing
  • change or problem with discharge of semen
  • chills
  • cold sweats
  • confusion
  • cough
  • cracked, dry, or scaly skin
  • crying
  • decreased weight
  • diarrhea
  • difficulty with moving
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • ear drainage
  • earache or pain in the ear
  • excess air or gas in the stomach or intestines
  • feeling of warmth, redness of the face, neck, arms, and occasionally, upper chest
  • feeling unusually cold
  • frequent urination
  • general feeling of discomfort or illness
  • groin pain
  • increased or sudden sweating
  • joint pain
  • loss of appetite
  • mood swings
  • muscle aches, cramping, pains, or stiffness
  • pain or burning with urination
  • passing gas
  • shivering
  • sinus headache
  • sleep disorder
  • swelling of the skin
  • swollen joints
  • swollen, tender prostate

For Healthcare Professionals

Applies to atomoxetine: oral capsule


Very common (10% or more): Dry mouth (up to 35%), nausea (up to 26%), abdominal pain/discomfort (up to 18%), constipation (up to 11%), vomiting (up to 11%)
Common (1% to 10%): Dyspepsia, gastroenteritis, diarrhea, flatulence[Ref]


Very common (10% or more): Decreased appetite (up to 24%)
Common (1% to 10%): Decreased weight, anorexia[Ref]


Very common (10% or more): Increased heart rate (up to 23.4%), increased blood pressure (up to 21.5%)
Common (1% to 10%): Orthostatic hypotension, palpitations, flushing/hot flush, sinus tachycardia, tachycardia
Uncommon (0.1% to 1%): QT interval prolongation
Rare (less than 0.1%): Raynaud's phenomenon and/or peripheral vascular instability
Frequency not reported: Myocardial infarction[Ref]


Very common (10% or more): Erectile dysfunction (up to 21%)
Common (1% to 10%): Dysmenorrhea, delayed ejaculation/ejaculation disorder/ejaculation failure, sexual dysfunction, impotence, prostatitis, abnormal orgasm, irregular menstruation, testicular pain, male genital pain
Postmarketing reports: Priapism, male pelvic pain[Ref]

Nervous system

Very common (10% or more): Headache (up to 19%), somnolence/sedation (up to 11%)
Common (1% to 10%): Dizziness, tremor, syncope/syncope vasovagal, paraesthesia, feeling jittery, dysgeusia
Uncommon (0.1% to 1%): Seizures, hypoesthesia
Frequency not reported: Stroke[Ref]


Very common (10% or more): Insomnia (up to 19%)
Common (1% to 10%): Aggression/hostility, irritability, mood swings, depression/depressed mood, early morning awakening, abnormal dreams, decreased libido, sleep disorder, agitation, anxiety
Uncommon (0.1% to 1%): Suicide-related behavior (suicide attempts, suicidal ideation), psychotic/manic symptoms (e.g., hallucinations, delusional thinking, mania), restlessness, emotional lability, generalized anxiety disorder
Frequency not reported: Panic attacks, impulsivity, akathisia, hypomania
Postmarketing reports: Tics, libido changes, sensory disturbances, completed suicide[Ref]


Very common (10% or more): Hyperhidrosis (up to 15%)
Common (1% to 10%): Rash, excoriation, dermatitis, pruritus
Uncommon (0.1% to 1%): Urticaria[Ref]


Very common (10% or more): Fatigue (up to 10%)
Common (1% to 10%): Unexpected therapeutic response, chills, thirst, peripheral coldness/feeling cold, influenza, pyrexia, rigors, lethargy, asthenia, chest pain
Frequency not reported: Delayed growth (height and weight), sudden death[Ref]


Common (1% to 10%): Urinary retention, urinary hesitation/decreased urine flow, dysuria, pollakiuria
Uncommon (0.1% to 1%): Micturition urgency, enuresis[Ref]


Common (1% to 10%): Conjunctivitis, mydriasis, blurred vision[Ref]


Common (1% to 10%): Upper respiratory tract infection
Uncommon (0.1% to 1%): Pharyngitis, dyspnea
Frequency not reported: Pharyngolaryngeal pain, oropharyngeal pain[Ref]


Uncommon (0.1% to 1%): Increased blood bilirubin
Rare (less than 0.1%): Liver failure, abnormal/increased liver function tests, jaundice, hepatitis, liver injury, acute hepatic failure[Ref]


Uncommon (0.1% to 1%): Allergic reactions (anaphylactic reactions, angioneurotic edema, urticarial, rash)[Ref]


Uncommon (0.1% to 1%): Muscle spasms
Frequency not reported: Back pain
Postmarketing reports: Rhabdomyolysis[Ref]


1. "Product Information. Strattera (atomoxetine)." Lilly, Eli and Company, Indianapolis, IN.

It is possible that some side effects of Strattera may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.