Polaramine Side Effects
Generic Name: dexchlorpheniramine
Note: This page contains side effects data for the generic drug dexchlorpheniramine. It is possible that some of the dosage forms included below may not apply to the brand name Polaramine.
For the Consumer
Applies to dexchlorpheniramine: controlled-release tablets, syrup
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking dexchlorpheniramine (the active ingredient contained in Polaramine)
Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.
For Healthcare Professionals
Applies to dexchlorpheniramine: compounding powder, oral syrup, oral tablet, oral tablet extended release
Gastrointestinal side effects have included dryness of mouth and throat, epigastric distress, anorexia, nausea, vomiting, diarrhea, and constipation.[Ref]
Genitourinary side effects have included urinary frequency, difficult urination, urinary frequency, and early menses.[Ref]
Hypersensitivity reactions have included drug rash, anaphylactic shock, and photosensitivity.[Ref]
Dermatologic side effects have included urticaria.[Ref]
General side effects have included excessive perspiration, chills, and dryness of nose.[Ref]
Hematologic side effects have included hemolytic anemia, thrombocytopenia, and agranulocytosis.[Ref]
Nervous system side effects have included sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesias, hysteria, neuritis, and convulsions.[Ref]
Ocular side effects have included blurred vision and diplopia.[Ref]
Otic side effects have included vertigo, tinnitus, and acute labyrinthitis.[Ref]
Respiratory side effects have included thickening of bronchial secretions, tightness of chest, wheezing, and nasal stiffness.[Ref]
1. "Product Information. Polaramine (dexchlorpheniramine)." Schering-Plough Corporation, Kenilworth, NJ.
2. Theunissen EL, Vermeeren A, Ramaekers JG "Repeated-dose effects of mequitazine, cetirizine and dexchlorpheniramine on driving and psychomotor performance." Br J Clin Pharmacol 61 (2006): 79-86
It is possible that some side effects of Polaramine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
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