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Dexchlorpheniramine Pregnancy and Breastfeeding Warnings

Medically reviewed by Last updated on Mar 7, 2023.

Dexchlorpheniramine is also known as: Polaramine, Polaramine Repetabs, Polmon, Ryclora

Dexchlorpheniramine Pregnancy Warnings

Dexchlorpheniramine has been assigned to category B by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. Dexchlorpheniramine has limited data from the manufacturer to suggest a recommendation for use during pregnancy.

Antihistamine exposure during the last two weeks of pregnancy has been associated with general and retrolental fibroplasia in premature infants.

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Dexchlorpheniramine Breastfeeding Warnings

Dexchlorpheniramine is excreted into human milk. Side effects of antihistamine use have been described as a higher risk in infants, newborns, and premature babies than in the general population. The manufacturer recommends that due to the potential for serious adverse reactions in the nursing infant, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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References for pregnancy information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation." Philadelphia, PA: Lippincott Williams & Wilkins (2005):
  2. "Product Information. Polaramine (dexchlorpheniramine)." Schering-Plough Corporation (2006):

References for breastfeeding information

  1. "Product Information. Polaramine (dexchlorpheniramine)." Schering-Plough Corporation (2006):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.