Mometasone / Olopatadine Nasal Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 15, 2025.

Applies to mometasone/olopatadine nasal: nasal spray.

Precautions

It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly and to check for unwanted effects.

If your or your child's symptoms do not improve within a few days or if they become worse, check with your doctor.

This medicine may increase your risk of having problems with your nose. Check with your doctor right away if you or your child have bloody mucus, sores inside the nose, or unexplained nosebleeds while you are using this medicine.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that makes you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, medicine for seizures, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Even if used at bedtime, it may cause some people to feel drowsy or less alert on arising. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

This medicine may cause fungus infection of the mouth or throat (thrush). Tell your doctor right away if you have white patches in the mouth or throat, or pain when eating or swallowing.

Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after treatment. Your doctor may want your eyes be checked by an ophthalmologist (eye doctor).

If you or your child have difficulty with breathing, or any allergic reaction to this medicine, check with your doctor right away.

Avoid close contact with anyone who has chickenpox or measles if you have never had these conditions before. This is especially important for children. Tell your doctor right away if you think you have been exposed to chickenpox or measles.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you or your child have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or weight loss.

This medicine may cause children to grow more slowly than usual. Talk to your child's doctor if you have any concerns.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects

Along with its needed effects, mometasone/olopatadine nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mometasone / olopatadine nasal:

Other side effects

Some side effects of mometasone / olopatadine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to mometasone / olopatadine nasal: nasal spray.

General adverse events

The most common adverse reactions were dysgeusia (substance-specific unpleasant taste), epistaxis, and nasal discomfort.^[Ref]

Dermatologic

• Rare (0.01% to 0.1%): Laceration^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea
• Uncommon (0.1% to 1%): Dry mouth, abdominal pain, nausea
• Rare (0.01% to 0.1%): Constipation, sore tongue^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection
• Rare (0.01% to 0.1%): Bacterial vaginosis^[Ref]

Hypersensitivity

Corticosteroids:

• Frequency not reported: Hypersensitivity (including anaphylactic reactions, angioedema, bronchospasm, dyspnea)

Mometasone nasal:

• Frequency not reported: Hypersensitivity reactions (including wheezing)^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain

Nasal corticosteroids:

• Frequency not reported: Growth retardation in children/reduction in growth velocity in pediatric patients^[Ref]

Nervous system

• Common (1% to 10%): Dysgeusia (unpleasant taste), headache
• Uncommon (0.1% to 1%): Dizziness, somnolence, lethargy
• Rare (0.01% to 0.1%): Migraine^[Ref]

Ocular

• Rare (0.01% to 0.1%): Blurred vision, dry eye, eye discomfort

Corticosteroids:

• Frequency not reported: Cataracts, glaucoma, increased intraocular pressure^[Ref]

Other

• Common (1% to 10%): Procedural pain
• Uncommon (0.1% to 1%): Fatigue
• Rare (0.01% to 0.1%): Ear pain^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Insomnia
• Rare (0.01% to 0.1%): Anxiety, depression^[Ref]

Respiratory

• Common (1% to 10%): Epistaxis, nasal discomfort, upper respiratory infection, viral upper respiratory tract infection, cough, bronchitis, streptococcal pharyngitis
• Uncommon (0.1% to 1%): Nasal dryness, nasal inflammation, oropharyngeal pain, throat irritation, sneezing
• Rare (0.01% to 0.1%): Nasal mucosal disorder

Corticosteroids:

• Frequency not reported: Pharyngitis, upper respiratory tract infection, nasal septum perforation

Mometasone nasal:

• Frequency not reported: Localized Candida albicans infections of the nose and pharynx

Nasal antihistamines:

• Frequency not reported: Nasal ulceration, nasal septal perforation^[Ref]

See also:

Further information

Mometasone/olopatadine nasal side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

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