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Mixed grass pollens allergen extract Side Effects

For the Consumer

Applies to mixed grass pollens allergen extract: sublingual tablet

Along with its needed effects, mixed grass pollens allergen extract may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mixed grass pollens allergen extract:

More common
  • Congestion
  • cough
  • difficulty with breathing
  • fever
  • itching ears, mouth, and tongue
  • noisy breathing
  • sore throat
  • swelling of the mouth
  • swollen glands
  • tightness in the chest
Less common
  • Body aches or pain
  • chills
  • headache
  • hives or welts, itching, or skin rash
  • loss of voice
  • numbness or tingling feeling around the mouth
  • redness of the skin
  • runny nose or sneezing
  • swelling of the lips or tongue
  • unusual tiredness or weakness
Incidence not known
  • Difficulty swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, irregular, pounding, or racing heartbeat or pulse
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the face, neck, arms, and occasionally, upper chest
  • sweating
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin

Some side effects of mixed grass pollens allergen extract may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Acid or sour stomach
  • belching
  • stomach discomfort, upset, or pain
Less common or rare Incidence not known

For Healthcare Professionals

Applies to mixed grass pollens allergen extract: sublingual tablet


The most common side effects reported were oral pruritus, throat irritation, ear pruritus, mouth edema, tongue pruritus, cough, oropharyngeal pain.[Ref]


Postmarketing reports: Anaphylactic reaction, oral allergy syndrome, angioedema[Ref]


Very common (10% or more): Throat irritation (22%)
Common (1% to 10%): Cough, oropharyngeal pain, pharyngeal edema, tonsillitis, upper respiratory tract infection, asthma, dysphonia
Postmarketing reports: Dyspnea, laryngeal edema, stridor, wheezing, exacerbation of asthma, oropharyngeal blistering[Ref]


Postmarketing reports: Flushing, eosinophilic myocarditis, palpitations, tachycardia, hypotension, circulatory collapse, pallor, peripheral vascular disorder, chest discomfort[Ref]


Common (1% to 10%): Urticaria, atopic dermatitis
Postmarketing reports: Rash, pruritus[Ref]


Postmarketing reports: Autoimmune thyroiditis[Ref]


Very common (10% or more): Oral pruritus (25.1%)
Common (1% to 10%): Mouth edema, tongue pruritus, lip edema, oral paresthesia, abdominal pain, dyspepsia, tongue edema, oral hypoesthesia, stomatitis, dysphagia, nausea, vomiting, esophageal pain, gastritis, gastroesophageal reflux, lip pruritus
Postmarketing reports: Diarrhea, eosinophilic esophagitis, salivary gland enlargement and/or hypersecretion, dry mouth, dry eye[Ref]


Postmarketing reports: Lymphoadenopathy, increased eosinophilic count[Ref]


Postmarketing reports: Decreased weight[Ref]

Nervous system

Postmarketing reports: Loss of consciousness, headache, somnolence, dizziness[Ref]


Common (1% to 10%): Ear pruritus
Postmarketing reports: Malaise, face edema, tinnitus, asthenia, influenza-like illness[Ref]


Postmarketing reports: Anxiety[Ref]


1. "Product Information. Oralair (mixed grass pollens allergen extract)." Greer Laboratories Inc, Lenoir, NC.

Some side effects of mixed grass pollens allergen extract may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.