Skip to Content

Meclomen Side Effects

Generic Name: meclofenamate

Note: This page contains information about the side effects of meclofenamate. Some of the dosage forms included on this document may not apply to the brand name Meclomen.

For the Consumer

Applies to meclofenamate: oral capsules

Side effects include:

Diarrhea, nausea with or without vomiting, other GI disorders, abdominal pain, flatulence, pyrosis, dizziness, headache, rash.

For Healthcare Professionals

Applies to meclofenamate: compounding powder, oral capsule


The most frequently reported side effects were gastrointestinal in nature and included diarrhea, nausea with or without vomiting, and abdominal pain.[Ref]


Very common (10% or more): Diarrhea (up to 33%), nausea (11%)
Common (1% to 10%): Vomiting, abdominal pain, pyrosis, flatulence, constipation, stomatitis, peptic ulcer
Frequency not reported: Colitis, bleeding, perforation, ulcer, paralytic ileus[Ref]


Common (1% to 10%): Rash, urticaria, pruritus
Frequency not reported: Erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, erythema nodosum, hair loss[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness
Frequency not reported: Paresthesia, taste disturbance[Ref]


Common (1% to 10%): Edema, tinnitus
Frequency not reported: Malaise, fatigue[Ref]


Frequency not reported: Palpitations[Ref]


Frequency not reported: Neutropenia, thrombocytopenic purpura, leukopenia, agranulocytosis, hemolytic anemia, eosinophilia, hemoglobin decreased, hematocrit decreased[Ref]


Frequency not reported: Liver function tests abnormal, cholestatic jaundice[Ref]


Frequency not reported: Renal failure[Ref]


Common (1% to 10%): Anorexia[Ref]


Frequency not reported: Vision blurred, visual acuity decreased, temporary vision loss, reversible color vision loss, macular fibrosis, macular edema, perimacular edema, conjunctivitis, iritis[Ref]


Frequency not reported: Depression, insomnia[Ref]


Frequency not reported: Nocturia[Ref]


Frequency not reported: Lupus-like syndrome[Ref]


Frequency not reported: Serum sickness-like syndrome


1. "Product Information. Meclofenamate Sodium (meclofenamate)." Mylan Pharmaceuticals Inc, Morgantown, WV.

Not all side effects for Meclomen may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.