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Meclomen Side Effects

Generic Name: meclofenamate

Note: This document contains side effect information about meclofenamate. Some of the dosage forms listed on this page may not apply to the brand name Meclomen.

For the Consumer

Applies to meclofenamate: oral capsules

Side effects include:

Diarrhea, nausea with or without vomiting, other GI disorders, abdominal pain, flatulence, pyrosis, dizziness, headache, rash.

For Healthcare Professionals

Applies to meclofenamate: compounding powder, oral capsule


The most frequently reported side effects were gastrointestinal in nature and included diarrhea, nausea with or without vomiting, and abdominal pain.[Ref]


Very common (10% or more): Diarrhea (up to 33%), nausea (11%)
Common (1% to 10%): Vomiting, abdominal pain, pyrosis, flatulence, constipation, stomatitis, peptic ulcer
Frequency not reported: Colitis, bleeding, perforation, ulcer, paralytic ileus[Ref]


Common (1% to 10%): Rash, urticaria, pruritus
Frequency not reported: Erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, erythema nodosum, hair loss[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness
Frequency not reported: Paresthesia, taste disturbance[Ref]


Common (1% to 10%): Edema, tinnitus
Frequency not reported: Malaise, fatigue[Ref]


Frequency not reported: Palpitations[Ref]


Frequency not reported: Neutropenia, thrombocytopenic purpura, leukopenia, agranulocytosis, hemolytic anemia, eosinophilia, hemoglobin decreased, hematocrit decreased[Ref]


Frequency not reported: Liver function tests abnormal, cholestatic jaundice[Ref]


Frequency not reported: Renal failure[Ref]


Common (1% to 10%): Anorexia[Ref]


Frequency not reported: Vision blurred, visual acuity decreased, temporary vision loss, reversible color vision loss, macular fibrosis, macular edema, perimacular edema, conjunctivitis, iritis[Ref]


Frequency not reported: Depression, insomnia[Ref]


Frequency not reported: Nocturia[Ref]


Frequency not reported: Lupus-like syndrome[Ref]


Frequency not reported: Serum sickness-like syndrome


1. "Product Information. Meclofenamate Sodium (meclofenamate)." Mylan Pharmaceuticals Inc, Morgantown, WV.

Some side effects of Meclomen may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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