Intal Side Effects

Generic name: cromolyn

Medically reviewed by Drugs.com. Last updated on Jul 3, 2025.

Note: This document contains side effect information about cromolyn. Some dosage forms listed on this page may not apply to the brand name Intal.

For healthcare professionals

Applies to cromolyn: compounding powder, inhalation aerosol with adapter, inhalation solution, nasal spray, oral capsule, oral solution.

General adverse events

Adverse reactions following use of this drug are rare; headache and diarrhea have been reported following oral use, while cough, nasal congestion, sneezing and wheezing have been reported with oral inhalation.^[Ref]

Hypersensitivity

• Postmarketing reports: Anaphylaxis, laryngeal edema^[Ref]

Respiratory

• Frequency not reported: Pharyngitis, dyspnea, cough, nasal congestion, sneezing, wheezing, nasal itching, nose bleed, nose burning
• Postmarketing reports: Bronchospasm, pulmonary infiltrates with eosinophilia, hoarseness^[Ref]

Hematologic

• Frequency not reported: Polycythemia, neutropenia, pancytopenia
• Postmarketing reports: Anemia^[Ref]

Genitourinary

• Postmarketing reports: Dysuria, urinary frequency^[Ref]

Dermatologic

• Rare (less than 0.1%): Pruritus, rash
• Frequency not reported: Urticaria/angioedema, erythema/burning, photosensitivity, purpura
• Postmarketing reports: Photodermatitis, exfoliative dermatitis^[Ref]

Gastrointestinal

• Rare (0.01% to 0.1%): Abdominal pain, nausea,
• Frequency not reported: Diarrhea, constipation, dyspepsia, flatulence, glossitis, stomatitis, vomiting, dysphagia, oesophagospasm, unpleasant taste, stomachache, mild throat irritation
• Postmarketing reports: Swollen parotid gland^[Ref]

Hepatic

• Frequency not reported: Abnormal hepatic function test^[Ref]

Cardiovascular

• Frequency not reported: Flushing, tachycardia, premature ventricular contractions, palpitations, chest pain
• Postmarketing reports: Periarteritic vasculitis, pericarditis^[Ref]

Musculoskeletal

• Rare (less than 0.1%): Myalgia
• Frequency not reported: Arthralgia, stiffness/weakness of legs, lupus erythematosus syndrome
• Postmarketing reports: Joint swelling and pain, polymyositis^[Ref]

Nervous system

• Rare (0.01% to 0.1%): Headache
• Frequency not reported: Dizziness, hypoesthesia, paresthesia, migraine, convulsions
• Postmarketing reports: Peripheral neuritis^[Ref]

Psychiatric

• Frequency not reported: Psychosis, anxiety, depression, hallucinations, behavior change, insomnia, nervousness^[Ref]

Other

• Frequency not reported: Fatigue, malaise, tinnitus
• Postmarketing reports: Vertigo^[Ref]

Ocular

• Postmarketing reports: Lacrimation^[Ref]

See also:

Further information

Intal side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer