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Finacea Side Effects

Generic Name: azelaic acid topical

Note: This document contains side effect information about azelaic acid topical. Some of the dosage forms listed on this page may not apply to the brand name Finacea.

For the Consumer

Applies to azelaic acid topical: topical cream, topical foam, topical gel/jelly

Along with its needed effects, azelaic acid topical (the active ingredient contained in Finacea) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking azelaic acid topical:

More common
  • Burning, stinging, or tingling of the skin
  • dryness, itching, peeling, or redness of the skin
Less common
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • scaling, severe redness, soreness, or swelling of the skin
Incidence not known
  • Fast heartbeat
  • fever
  • hives, itching, or skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • swelling of the eyes
  • tightness in the chest
  • troubled breathing or swallowing

Some side effects of azelaic acid topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare
  • Change in skin color at treated areas
Incidence not known
  • Blurred vision
  • eye pain
  • eye redness
  • tearing

For Healthcare Professionals

Applies to azelaic acid topical: compounding powder, topical cream, topical foam, topical gel, topical kit

Local

Local irritation occurs during the first few weeks of treatment and generally presents as pruritus, scaling, burning and tingling.[Ref]

Respiratory

Respiratory side effects have included worsening of asthma in rare instances.[Ref]

Dermatologic

Dermatological side effects have included pruritus, burning, stinging, and tingling in 1% to 5% of patients using the 20% cream and up to 20% of patients using the 15% gel. Other side effects have included erythema, dryness, rash, peeling, irritation, dermatitis, edema, xerosis, photosensitivity, and contact dermatitis. There have been rare reports of vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening and exacerbation of recurrent herpes labialis in some patients.[Ref]

References

1. "Product Information. Finacea (azelaic acid topical)." Berlex Laboratories, Richmond, CA.

2. Fitton A, Goa KL "Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders." Drugs 41 (1991): 780-98

3. Maddin S "A comparison of topical azelaic acid 20% cream and topical metronidazole 0.75% cream in the treatment of patients with papulopustular rosacea." J Am Acad Dermatol 40 (1999): 961-5

4. Gupta AK, Gover MD "Azelaic acid (15% gel) in the treatment of acne rosacea." Int J Dermatol 46 (2007): 533-8

5. "Product Information. Azelex (azelaic acid)." Allergan Inc, Irvine, CA.

6. Thiboutot D, Thieroff-Ekerdt R, Graupe K "Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: Results from two vehicle-controlled, randomized phase III studies." J Am Acad Dermatol 48 (2003): 836-45

Some side effects of Finacea may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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