Extendryl JR Side Effects
Generic name: chlorpheniramine / methscopolamine / phenylephrine
Note: This document provides detailed information about Extendryl JR Side Effects associated with chlorpheniramine / methscopolamine / phenylephrine. Some dosage forms listed on this page may not apply specifically to the brand name Extendryl JR.
Applies to chlorpheniramine / methscopolamine / phenylephrine: oral tablet chewable.
Important warnings
This medicine can cause some serious health issues
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days.
A dangerous drug interaction could occur.
MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Get emergency medical help if you have any of these signs of an allergic reaction while taking chlorpheniramine/methscopolamine/phenylephrine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
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little or no urinating;
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fast, pounding, or irregular heartbeats;
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pale skin, weakness, feeling short of breath; or
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tremors, hallucinations, severe anxiety.
Common side effects may include:
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blurred vision, headache, dizziness;
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dry mouth, nose, or throat;
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nausea; or
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feeling nervous or restless.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For healthcare professionals
Applies to chlorpheniramine / methscopolamine / phenylephrine: oral capsule extended release, oral liquid, oral suspension extended release, oral syrup, oral tablet, oral tablet chewable, oral tablet chewable extended release, oral tablet extended release.
General
General side effects of phenylephrine have included pallor and weakness.[Ref]
Cardiovascular
Cardiovascular side effects of phenylephrine have included palpitations, arrhythmias, and cardiovascular collapse with hypotension.[Ref]
Psychiatric
Psychiatric side effects of phenylephrine have included hallucinations, fear, and anxiety.[Ref]
Gastrointestinal
Gastrointestinal side effects of phenylephrine have included nausea. Antihistamines such as chlorpheniramine and anticholinergics such as methscopolamine may cause excessive dryness of the nose, throat, and mouth.[Ref]
Respiratory
Respiratory side effects of phenylephrine have included respiratory difficulty.[Ref]
Genitourinary
Genitourinary side effects of phenylephrine have included dysuria.[Ref]
Nervous system
Nervous system side effects of phenylephrine have included headache, dizziness, nervousness, restlessness, tremor, insomnia, convulsions, and central nervous system depression. Antihistamines such as chlorpheniramine and anticholinergics such as methscopolamine may cause drowsiness and dizziness.[Ref]
Ocular
Ocular side effects including blurred vision may be caused by antihistamines such as chlorpheniramine and anticholinergics such as methscopolamine.[Ref]
References
1. (2002) "Product Information. Ah-Chew D (phenylephrine)." WE Pharmaceuticals Inc
2. (2022) "Product Information. Drize (chlorpheniramine/methscopolamine/PE)." King Pharmaceuticals Inc
3. (1998) "PDR Generics." Montvale, NJ: Medical Economics
More about Extendryl JR (chlorpheniramine / methscopolamine / phenylephrine)
- Check interactions
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Patient resources
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Further information
Extendryl JR side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.