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Chlorpheniramine / Methscopolamine / Phenylephrine Dosage

Medically reviewed on November 20, 2017.

Applies to the following strengths: 2 mg-0.625 mg-10 mg/5 mL; 8 mg-2.5 mg-20 mg; 2 mg-1.25 mg-10 mg/5 mL; 2 mg-1.25 mg-10 mg; 4 mg-1.25 mg-10 mg; 12 mg-2.5 mg-20 mg; ages 12 years and older; 2 mg-0.75 mg-8 mg/5 mL; 2 mg-0.75 mg-10 mg/5 mL; 4 mg-1.25 mg-10 mg/ 5 mL; 8 mg-1.25 mg-20 mg; 2 mg-1.5 mg-10 mg/5 mL; 8 mg-2.5 mg-25 mg; 2 mg-1.25 mg-15 mg; 2 mg-1.5 mg-10 mg; ages 6 years and older; 8 mg-2.5 mg-40 mg; 12 mg-2 mg-40 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nasal Congestion

Tablets:
chlorpheniramine/methscopolamine/PE 8 mg-1.25 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-25 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2.5 mg-20 mg extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-20 mg oral tablet, extended release:
1 tablet orally twice a day, not to exceed 2 doses per day.

chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg oral tablet or chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg oral tablet, chewable: 1 to 2 tablets orally every 12 hours, not to exceed 4 tablets per day.

chlorpheniramine/methscopolamine/PE varying strength oral tablet, extended release:
chlorpheniramine/methscopolamine/PE 2.5 mg-40 mg extended release: 1 tablet orally in the morning and
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-10 mg extended release: 1 tablet orally in the evening.

chlorpheniramine/methscopolamine/PE ages 6 years and older oral tablet, extended release
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg extended release: 1 or 2 tablets orally in the morning and
chlorpheniramine/methscopolamine/PE 2 mg--1.5 mg extended release: 1 or 2 tablets orally in the evening.

Liquid:
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg/5 mL extended release: 5 to 10 mL orally every 12 hours daily.
chlorpheniramine/methscopolamine/PE 2 mg-0.625 mg-10 mg/5 mL oral syrup 10 mL orally every 4-6 hours, not to exceed 4 doses per day.
chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg/5 mL oral syrup: 5 to 10 mL orally every 3-4 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-8 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-10 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg/5 mL: 5 to 10 mL orally every 3 or 4 hours daily.

Usual Adult Dose for Rhinitis

Tablets:
chlorpheniramine/methscopolamine/PE 8 mg-1.25 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-25 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2.5 mg-20 mg extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-20 mg oral tablet, extended release:
1 tablet orally twice a day, not to exceed 2 doses per day.

chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg oral tablet or chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg oral tablet, chewable: 1 to 2 tablets orally every 12 hours, not to exceed 4 tablets per day.

chlorpheniramine/methscopolamine/PE varying strength oral tablet, extended release:
chlorpheniramine/methscopolamine/PE 2.5 mg-40 mg extended release: 1 tablet orally in the morning and
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-10 mg extended release: 1 tablet orally in the evening.

chlorpheniramine/methscopolamine/PE ages 6 years and older oral tablet, extended release
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg extended release: 1 or 2 tablets orally in the morning and
chlorpheniramine/methscopolamine/PE 2 mg--1.5 mg extended release: 1 or 2 tablets orally in the evening.

Liquid:
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg/5 mL extended release: 5 to 10 mL orally every 12 hours daily.
chlorpheniramine/methscopolamine/PE 2 mg-0.625 mg-10 mg/5 mL oral syrup 10 mL orally every 4-6 hours, not to exceed 4 doses per day.
chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg/5 mL oral syrup: 5 to 10 mL orally every 3-4 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-8 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-10 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg/5 mL: 5 to 10 mL orally every 3 or 4 hours daily.

Usual Pediatric Dose for Nasal Congestion

12 yrs and older:
Tablets:
chlorpheniramine/methscopolamine/PE 8 mg-1.25 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-25 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2.5 mg-20 mg extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-20 mg oral tablet, extended release:
1 tablet orally twice a day, not to exceed 2 doses per day.

chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg oral tablet or chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg oral tablet, chewable: 1 to 2 tablets orally every 12 hours, not to exceed 4 tablets per day.

chlorpheniramine/methscopolamine/PE varying strength oral tablet, extended release:
chlorpheniramine/methscopolamine/PE 2.5 mg-40 mg extended release: 1 tablet orally in the morning and
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-10 mg extended release: 1 tablet orally in the evening.

chlorpheniramine/methscopolamine/PE ages 6 years and older oral tablet, extended release
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg extended release: 1 or 2 tablets orally in the morning and
chlorpheniramine/methscopolamine/PE 2 mg--1.5 mg extended release: 1 or 2 tablets orally in the evening.

Liquid:
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg/5 mL extended release: 5 to 10 mL orally every 12 hours daily.
chlorpheniramine/methscopolamine/PE 2 mg-0.625 mg-10 mg/5 mL oral syrup 10 mL orally every 4-6 hours, not to exceed 4 doses per day.
chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg/5 mL oral syrup: 5 to 10 mL orally every 3-4 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-8 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-10 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg/5 mL: 5 to 10 mL orally every 3 or 4 hours daily.

6 yrs to 11 yrs:
Liquid:
chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg/5 mL: 2.5 to 5 mL orally every 4 hours daily.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-8 mg/5 mL: 5 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-10 mg/5 mL: 5 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.

chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg/5 mL, extended release 2.5 to 5 mL orally every 12 hours daily.

Chew tab:
chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-15 mg chewable: 1 tablet orally every 4 hours not to exceed 4 tablets per day.

Tablets:
chlorpheniramine/methscopolamine/PE 8 mg-1.25 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-25 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2.5 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2 mg-40 mg, extended release:
1/2 tablet orally twice daily, not to exceed 2 doses per day.

chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg oral tablet, chewable: 1/2 to 1 tablet orally every 12 hours, not to exceed 2 tablets per day.

chlorpheniramine/methscopolamine/PE ages 6 years and older oral tablet, extended release
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg extended release: 1/2 to 1 tablet orally in the morning and
chlorpheniramine/methscopolamine/PE 2 mg--1.5 mg extended release: 1/2 to 1 tablet orally in the evening.

Usual Pediatric Dose for Rhinitis

12 yrs and older:
Tablets:
chlorpheniramine/methscopolamine/PE 8 mg-1.25 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-25 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2.5 mg-20 mg extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-20 mg oral tablet, extended release:
1 tablet orally twice a day, not to exceed 2 doses per day.

chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg oral tablet or chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg oral tablet, chewable: 1 to 2 tablets orally every 12 hours, not to exceed 4 tablets per day.

chlorpheniramine/methscopolamine/PE varying strength oral tablet, extended release:
chlorpheniramine/methscopolamine/PE 2.5 mg-40 mg extended release: 1 tablet orally in the morning and
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-10 mg extended release: 1 tablet orally in the evening.

chlorpheniramine/methscopolamine/PE ages 6 years and older oral tablet, extended release
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg extended release: 1 or 2 tablets orally in the morning and
chlorpheniramine/methscopolamine/PE 2 mg--1.5 mg extended release: 1 or 2 tablets orally in the evening.

Liquid:
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg/5 mL extended release: 5 to 10 mL orally every 12 hours daily.
chlorpheniramine/methscopolamine/PE 2 mg-0.625 mg-10 mg/5 mL oral syrup 10 mL orally every 4-6 hours, not to exceed 4 doses per day.
chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg/5 mL oral syrup: 5 to 10 mL orally every 3-4 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-8 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-10 mg/5 mL: 10 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg/5 mL: 5 to 10 mL orally every 3 or 4 hours daily.

6 yrs to 11 yrs:
Liquid:
chlorpheniramine/methscopolamine/PE 4 mg-1.25 mg-10 mg/5 mL: 2.5 to 5 mL orally every 4 hours daily.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-8 mg/5 mL: 5 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.
chlorpheniramine/methscopolamine/PE 2 mg-0.75 mg-10 mg/5 mL: 5 mL orally every 4 to 6 hours daily not to exceed 4 doses in 24 hours.

chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg/5 mL, extended release 2.5 to 5 mL orally every 12 hours daily.

Chew tab:
chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-15 mg chewable: 1 tablet orally every 4 hours not to exceed 4 tablets per day.

Tablets:
chlorpheniramine/methscopolamine/PE 8 mg-1.25 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-25 mg, extended release or
chlorpheniramine/methscopolamine/PE 8 mg-2.5 mg-40 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2.5 mg-20 mg, extended release or
chlorpheniramine/methscopolamine/PE 12 mg-2 mg-40 mg, extended release:
1/2 tablet orally twice daily, not to exceed 2 doses per day.

chlorpheniramine/methscopolamine/PE 2 mg-1.25 mg-10 mg oral tablet, chewable: 1/2 to 1 tablet orally every 12 hours, not to exceed 2 tablets per day.

chlorpheniramine/methscopolamine/PE ages 6 years and older oral tablet, extended release
chlorpheniramine/methscopolamine/PE 2 mg-1.5 mg-10 mg extended release: 1/2 to 1 tablet orally in the morning and
chlorpheniramine/methscopolamine/PE 2 mg--1.5 mg extended release: 1/2 to 1 tablet orally in the evening.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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