Skip to main content

Budesonide / formoterol Side Effects

Medically reviewed by Last updated on Oct 19, 2023.

Applies to budesonide / formoterol: inhalation aerosol liquid.

Serious side effects

Along with its needed effects, budesonide/formoterol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking budesonide / formoterol:

More common

Less common


Incidence not known

Get emergency help immediately if any of the following symptoms of overdose occur while taking budesonide / formoterol:

Symptoms of overdose

Other side effects

Some side effects of budesonide / formoterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common


For Healthcare Professionals

Applies to budesonide / formoterol: inhalation aerosol.


General side effects have included oral candidiasis, and transient mild tremor and palpitations which tend to disappear within a few days of treatment.[Ref]

Nervous system

Very common (10% or more): Headache (up to 11.3%)

Common (1% to 10%): Tremor

Uncommon (0.1% to 1%): Dizziness, thirst tiredness

Very rare (less than 0.01%): taste disturbances[Ref]


Very common (10% or more): Nasopharyngitis (up to 10.5%), upper respiratory tract infection (up to 10.5%)

Common (1% to 10%): Sinusitis, nasal congestion, bronchitis, mild irritation in the throat, coughing, hoarseness, pneumonia

Rare (0.01% to 0.1%): Bronchospasm

Very rare (less than 0.01%): Paradoxical bronchospasm

Postmarketing reports: Dysphonia, cough, throat irritation[Ref]


Common (1% to 10%): Palpitations

Uncommon (0.1% to 1%): Tachycardia

Rare (0.01% to 0.1%): Cardiac arrhythmias, e.g. atrial fibrillation, supraventricular tachycardia, extrasystoles

Very rare (less than 0.01%): Angina pectoris, prolongation of QTc-interval, variations in blood pressure

Postmarketing reports: Atrial and ventricular tachyarrhythmias, hypotension, hypertension[Ref]


Common (1% to 10%): Pharyngolaryngeal pain, stomach discomfort, vomiting, oral candidiasis

Uncommon (0.1% to 1%): Nausea

Postmarketing reports: Oropharyngeal candidiasis[Ref]


Common (1% to 10%): Back pain,

Uncommon (0.1% to 1%): Muscle cramps[Ref]


Common (1% to 10%): Influenza[Ref]


Common (1% to 10%):

Uncommon (0.1% to 1%): Aggression, psychomotor hyperactivity, anxiety, sleep disorders

Very rare (less than 0.01%): Depression, behavioral changes

Postmarketing reports: Behavior disturbances, sleep disturbances, nervousness, agitation, depression, restlessness[Ref]


Uncommon (0.1% to 1%): Skin bruising[Ref]


Uncommon (0.1% to 1%): Weight gain

Rare (0.01% to 0.1%): Hypokalemia

Very rare (less than 0.01%): Hyperglycemia[Ref]


Uncommon (0.1% to 1%): Blurred vision

Very rare (less than 0.01%): Cataract, glaucoma

Frequency not reported: Central serous retinopathy

Postmarketing reports: Increased intraocular pressure[Ref]


Rare (less than 0.1%): Immediate and delayed hypersensitivity reactions, e.g. exanthema, urticaria, pruritus, dermatitis, angioedema and anaphylactic reaction[Ref]


Very rare (less than 0.01%): Cushing's syndrome, adrenal suppression, growth retardation, decrease in bone mineral density

Postmarketing reports: Hypercorticism, growth velocity reduction in pediatric patients[Ref]

Frequently asked questions


1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Product Information. Symbicort (budesonide-formoterol). Astra-Zeneca Pharmaceuticals. 2006.

3. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.