Skip to main content

Azopt Side Effects

Generic name: brinzolamide ophthalmic

Medically reviewed by Last updated on Jun 7, 2023.

Note: This document contains side effect information about brinzolamide ophthalmic. Some dosage forms listed on this page may not apply to the brand name Azopt.

Applies to brinzolamide ophthalmic: ophthalmic suspension.

Serious side effects of Azopt

Along with its needed effects, brinzolamide ophthalmic (the active ingredient contained in Azopt) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking brinzolamide ophthalmic:

More common

Less common


Incidence not known

Get emergency help immediately if any of the following symptoms of overdose occur while taking brinzolamide ophthalmic:

Symptoms of overdose

Other side effects of Azopt

Some side effects of brinzolamide ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common


For Healthcare Professionals

Applies to brinzolamide ophthalmic: ophthalmic suspension.


Common (1% to 10%): Blepharitis, dry eye, foreign body sensation, ocular hyperemia, ocular discharge, ocular discomfort, ocular keratitis, ocular pain, ocular pruritus, blurred vision, eye irritation

Uncommon (0.1% to 1%): Conjunctivitis, diplopia, eye fatigue, keratoconjunctivitis, lid margin crusting or sticky sensation, tearing, corneal erosion, punctate keratitis, keratopathy, corneal staining, corneal epithelium defect, corneal epithelium disorder, increased intraocular pressure, increased optic nerve cup/disc ratio, corneal edema, eye swelling, meibomianitis, glare, photophobia, photopsia, reduced visual acuity, allergic conjunctivitis, pterygium, scleral pigmentation, asthenopia, keratoconjunctivitis sicca, eye hypoesthesia, subconjunctival cyst, conjunctival hyperemia, eyelids pruritus

Frequency not reported: Corneal disorder, visual disturbance, eye allergy, madarosis, eyelid disorder, eyelid erythema[Ref]


Common (1% to 10%): Allergic reactions

Frequency not reported: Hypersensitivity[Ref]


Uncommon (0.1% to 1%): Pain, asthenia, fatigue, feeling abnormal, feeling jittery

Frequency not reported: Peripheral edema, malaise, medication residue[Ref]

Nervous system

Common (1% to 10%): Headache, dysgeusia, tinnitus

Uncommon (0.1% to 1%): Dizziness, hypertonia, somnolence, motor dysfunction, amnesia, memory impairment, paresthesia

Frequency not reported: Tremor, hypoesthesia, ageusia, vertigo[Ref]


Common (1% to 10%): Dermatitis

Uncommon (0.1% to 1%): Alopecia, urticaria, rash, maculo-papular rash, generalized pruritus, skin tightness[Ref]


Uncommon (0.1% to 1%): Diarrhea, dry mouth, dyspepsia, nausea, esophagitis, vomiting, upper abdominal pain, abdominal discomfort, stomach discomfort, flatulence, frequent bowel movements, gastrointestinal disorder, oral hypoesthesia, oral paresthesia[Ref]


Common (1% to 10%): Rhinitis

Uncommon (0.1% to 1%): Dyspnea, pharyngitis, nasopharyngitis, sinusitis, bronchial hyperactivity, cough, epistaxis, pharyngolaryngeal pain, throat irritation, nasal congestion, upper respiratory tract congestion, postnasal drip, rhinorrhea, sneezing, nasal dryness

Frequency not reported: Asthma[Ref]


Uncommon (0.1% to 1%): Cardio-respiratory distress, angina pectoris, bradycardia, irregular palpitations

Frequency not reported: Arrhythmia, tachycardia, hypertension, increased blood pressure, increased heart rate[Ref]


Uncommon (0.1% to 1%): Back pain, muscle spasms, myalgia

Frequency not reported: Arthralgia, pain in extremity[Ref]


Uncommon (0.1% to 1%): Kidney pain

Frequency not reported: Pollakiuria[Ref]


The most commonly reported adverse reactions were blurred vision and bitter, sour or unusual taste.[Ref]


Uncommon (0.1% to 1%): Decreased libido, erectile dysfunction[Ref]


Uncommon (0.1% to 1%): Decreased red blood cell count, increased blood chloride[Ref]


Frequency not reported: Abnormal liver function test[Ref]


Uncommon (0.1% to 1%): Apathy, depression, depressed mood, nightmare, insomnia, nervousness, irritability[Ref]


1. Product Information. Azopt (brinzolamide ophthalmic). Alcon Laboratories Inc. 2001;PROD.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

3. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.