Aspirin / Carisoprodol Side Effects

Medically reviewed by Drugs.com. Last updated on Oct 8, 2024.

Applies to aspirin / carisoprodol: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects. .

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Avoid driving, using machines, or do anything else that could be dangerous if you are not alert.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you are taking this medicine.

Do not stop using this medicine suddenly without first asking your doctor. You may need to slowly decrease your dose before stopping it completely.

This medicine may cause bleeding in your stomach or intestines. This problem can happen without warning signs. This is more likely if you have had a stomach ulcer in the past, if you drink alcohol regularly, if you are over 60 years of age, are in poor health, or are using certain other medicines (such as a blood thinner or nonsteroidal anti-inflammatory medicine [NSAIDs]).

This medicine may also cause a serious type of allergic reaction called anaphylaxis. Although this is rare, it may occur more often in patients who are allergic to aspirin or to any of the nonsteroidal anti-inflammatory drugs. Anaphylaxis can be life-threatening and requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face; very fast but irregular heartbeat or pulse; hive-like swellings on the skin; and puffiness or swellings of the eyelids or around the eyes. If these effects occur, get emergency help at once.

Using this medicine during late pregnancy can harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.

If your condition does not improve or become worse, check with your doctor. Do not use this medicine for more than 2 to 3 weeks (14 to 21 days) to treat pain unless your doctor has told you to.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects

Along with its needed effects, aspirin/carisoprodol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aspirin / carisoprodol:

Get emergency help immediately if any of the following symptoms of overdose occur while taking aspirin / carisoprodol:

Symptoms of overdose

• agitation or combativeness
• anxiety
• black, tarry stools
• bloody stools
• blue lips and fingernails
• change in consciousness
• cold, clammy skin
• confusion
• coughing that sometimes produces a pink frothy sputum
• decreased awareness or responsiveness
• decreased urination
• depression
• diarrhea
• difficult, fast, or noisy breathing, sometimes with wheezing
• dry mouth
• expressed fear of impending death
• extremely high fever or body temperature
• fainting
• fast or deep breathing
• fast, weak pulse
• hallucinations
• headache
• holding false beliefs that cannot be changed by fact
• irregular, fast or slow, or shallow breathing
• lethargy
• loss of consciousness
• loss of strength or energy
• muscle cramps
• muscle pain or weakness
• nausea
• pale or blue lips, fingernails, or skin
• pale, clammy skin
• severe sleepiness
• sunken eyes
• sweating
• swelling in the legs and ankles
• thirst
• unusual excitement, nervousness, or restlessness
• vomiting
• vomiting of blood or material that looks like coffee grounds
• wrinkled skin

Other side effects

Some side effects of aspirin / carisoprodol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to aspirin / carisoprodol: oral tablet.

General adverse events

The most commonly reported adverse reactions include dizziness, drowsiness, and gastrointestinal discomfort.^[Ref]

Psychiatric

• Frequency not reported: Drug dependence, withdrawal, abuse, misuse, criminal diversion, agitation, irritability, depressive reactions, insomnia^[Ref]

Withdrawal symptoms that have been reported following abrupt withdrawal after prolonged use have included: insomnia, vomiting, abdominal cramps, headache, tremors, muscle twitching, ataxia, hallucinations, and psychosis.^[Ref]

Gastrointestinal

Carisoprodol:

• Frequency not reported: Nausea, vomiting, epigastric discomfort

Aspirin:

• Frequency not reported: Bleeding, perforation, obstruction of stomach, small intestine or large intestine, epigastric discomfort, gastric and duodenal ulcers, gastritis, gastrointestinal erosions, abdominal pain, heartburn, vomiting, nausea, anorexia^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylaxis, anaphylactoid reactions^[Ref]

Aspirin

Nervous system

Carisoprodol:

• Frequency not reported: Sedation, drowsiness, dizziness, ataxia, tremor
• Postmarketing reports: Motor vehicle accidents, seizures

Aspirin:

• Frequency not reported: Intracranial hemorrhage^[Ref]

Cardiovascular

Carisoprodol:

• Frequency not reported: Tachycardia, postural hypotension, facial flushing, syncope^[Ref]

Dermatologic

Aspirin:

• Frequency not reported: Rash pruritus, purpura^[Ref]

Renal

Aspirin:

• Frequency not reported: Interstitial nephritis, acute renal failure^[Ref]

Hematologic

Carisoprodol:

• Frequency not reported: Leukopenia, pancytopenia^[Ref]

Hepatic

Aspirin:

• Frequency not reported: Elevated liver enzymes^[Ref]

Other

Carisoprodol:

• Frequency not reported: Vertigo

Aspirin:

• Frequency not reported: Tinnitus^[Ref]

Tinnitus may be a symptom of high serum salicylate levels.^[Ref]

See also:

Further information

Aspirin/carisoprodol side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer