Aspirin / Carisoprodol Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 21, 2024.

Applies to aspirin / carisoprodol: oral tablet.

Serious side effects

Along with its needed effects, aspirin/carisoprodol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aspirin / carisoprodol:

More common side effects

• burning feeling in the chest or stomach
• indigestion
• stomach upset
• tenderness in the stomach area

Less common side effects

• cough
• difficult or troubled breathing
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• noisy breathing
• shakiness and unsteady walk
• shortness of breath
• tightness in the chest
• unsteadiness, trembling, or other problems with muscle control or coordination

Incidence not known

• chills
• cold sweats
• confusion
• continuing ringing or buzzing or other unexplained noise in the ears
• difficulty with swallowing
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fast, pounding, or irregular heartbeat or pulse
• flushing or redness of the skin
• hearing loss
• hives
• itching
• painful or difficult urination
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• skin rash
• sore throat
• sores, ulcers, or white spots on the lips or in the mouth
• swollen glands
• unusual bleeding or bruising
• unusual tiredness or weakness
• unusually warm skin
• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur while taking aspirin / carisoprodol:

Symptoms of overdose

• agitation or combativeness
• anxiety
• black, tarry stools
• bloody stools
• blue lips and fingernails
• change in consciousness
• cold, clammy skin
• confusion
• coughing that sometimes produces a pink frothy sputum
• decreased awareness or responsiveness
• decreased urination
• depression
• diarrhea
• difficult, fast, or noisy breathing, sometimes with wheezing
• dry mouth
• expressed fear of impending death
• extremely high fever or body temperature
• fainting
• fast or deep breathing
• fast, weak pulse
• hallucinations
• headache
• holding false beliefs that cannot be changed by fact
• irregular, fast or slow, or shallow breathing
• lethargy
• loss of consciousness
• loss of strength or energy
• muscle cramps
• muscle pain or weakness
• nausea
• pale or blue lips, fingernails, or skin
• pale, clammy skin
• severe sleepiness
• sunken eyes
• sweating
• swelling in the legs and ankles
• thirst
• unusual excitement, nervousness, or restlessness
• vomiting
• vomiting of blood or material that looks like coffee grounds
• wrinkled skin

Other side effects

Some side effects of aspirin / carisoprodol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• drowsiness

Less common side effects

• feeling of constant movement of self or surroundings
• sensation of spinning

Rare side effects

• hyperventilation
• irritability
• shaking
• sleeplessness
• trouble sleeping
• unable to sleep

For healthcare professionals

Applies to aspirin / carisoprodol: oral tablet.

General adverse events

The most commonly reported adverse reactions include dizziness, drowsiness, and gastrointestinal discomfort.^[Ref]

Psychiatric

• Frequency not reported: Drug dependence, withdrawal, abuse, misuse, criminal diversion, agitation, irritability, depressive reactions, insomnia^[Ref]

Withdrawal symptoms that have been reported following abrupt withdrawal after prolonged use have included: insomnia, vomiting, abdominal cramps, headache, tremors, muscle twitching, ataxia, hallucinations, and psychosis.^[Ref]

Gastrointestinal

Carisoprodol:

• Frequency not reported: Nausea, vomiting, epigastric discomfort

Aspirin:

• Frequency not reported: Bleeding, perforation, obstruction of stomach, small intestine or large intestine, epigastric discomfort, gastric and duodenal ulcers, gastritis, gastrointestinal erosions, abdominal pain, heartburn, vomiting, nausea, anorexia^[Ref]

Hypersensitivity

• Frequency not reported: Anaphylaxis, anaphylactoid reactions^[Ref]

Aspirin

Nervous system

Carisoprodol:

• Frequency not reported: Sedation, drowsiness, dizziness, ataxia, tremor
• Postmarketing reports: Motor vehicle accidents, seizures

Aspirin:

• Frequency not reported: Intracranial hemorrhage^[Ref]

Cardiovascular

Carisoprodol:

• Frequency not reported: Tachycardia, postural hypotension, facial flushing, syncope^[Ref]

Dermatologic

Aspirin:

• Frequency not reported: Rash pruritus, purpura^[Ref]

Renal

Aspirin:

• Frequency not reported: Interstitial nephritis, acute renal failure^[Ref]

Hematologic

Carisoprodol:

• Frequency not reported: Leukopenia, pancytopenia^[Ref]

Hepatic

Aspirin:

• Frequency not reported: Elevated liver enzymes^[Ref]

Other

Carisoprodol:

• Frequency not reported: Vertigo

Aspirin:

• Frequency not reported: Tinnitus^[Ref]

Tinnitus may be a symptom of high serum salicylate levels.^[Ref]

Further information

Aspirin/carisoprodol side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer