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Aspirin / Carisoprodol Dosage

Medically reviewed on September 28, 2016.

Applies to the following strengths: 325 mg-200 mg

Usual Adult Dose for Muscle Spasm

1 to 2 tablets 4 times a day
Maximum daily dose: carisoprodol: 1600 mg; aspirin: 2600 mg
Duration of therapy: Up to 3 weeks

Comments:
-Use should be limited to short periods (up to 3 weeks) since acute, painful musculoskeletal conditions are generally of short duration and evidence of effectiveness beyond this time period has not been established.

Use: For the relief of discomfort associated with acute, painful musculoskeletal conditions.

Renal Dose Adjustments

Use with caution

Liver Dose Adjustments

Use with caution

Dose Adjustments

Patients with Reduced CYP450 2C19 Activity:
-Use with caution as higher exposure to carisoprodol and lower exposure to meprobamate is expected; the clinical significance of this is not known.

Precautions

Safety and efficacy have not been established in patients younger than 16 years or older than 65 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule: IV

Dialysis

Data not available

Other Comments

Administration advice:
-Duration of therapy should be limited to short-term treatment

General:
-Dependence, withdrawal, and abuse have been reported; the risk of abuse should be assessed prior to prescribing.
-Treatment duration should not exceed up to 2 to 3 weeks; if musculoskeletal symptoms persist, patients should be re-evaluated.

Monitoring:
-Monitor for sedation
-Monitor for signs of abuse and overdose

Patient advice:
-Patients should understand that this product contains aspirin and that aspirin may cause a wide range of gastrointestinal adverse reactions including potentially fatal events; patients should be informed of signs or symptoms to watch for and which require prompt medical attention.
-Patients should be advised that this drug may cause drowsiness and dizziness and that there have been reports of motor vehicle accidents following use; patients should be advised to avoid hazardous activities such as driving while taking this drug.
-Patients should be advised to avoid concomitant use with alcohol and to check with their health care professional before taking other CNS depressants.
-Patients should understand that this drug has been associated with cases of dependence, withdrawal, and abuse; use should be limited to less than 3 weeks duration.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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