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Versed (injection)

Generic Name: midazolam (injection) (mi DAZ oh lam)
Brand Name: Versed

Medically reviewed by Drugs.com on Jul 8, 2020 – Written by Cerner Multum

What is Versed?

Versed is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) sedative.

Versed is used to sedate a person who is having a minor surgery, dental work, or other medical procedure.

Versed is also used to sedate a patient who is under critical care and needs a mechanical ventilator (breathing machine).

Versed may also be used for purposes not listed in this medication guide.

Important Information

Versed can slow or stop your breathing, especially if you have recently used a narcotic (opioid) medication. This medicine is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.

Before you are treated with Versed, tell your doctor about all your medical conditions or allergies, and all the medicines you are using. Also make sure your doctor knows if you are pregnant or breastfeeding.

Before taking this medicine

You should not be treated with Versed if you are allergic to it, or if you have:

If possible before you receive Versed, tell your caregivers if you have ever had:

Versed can cause birth defects in an unborn baby, and generally should not be used during pregnancy.

Sedatives used during surgery may affect brain development in a child under 3, or an unborn baby whose mother receives Versed during late pregnancy. These effects may be more likely when a sedative is used for 3 hours or longer, or used for repeated procedures. Effects on brain development could cause learning or behavior problems later in life.

Negative brain effects from sedatives have been seen in animal studies. However, studies in human children receiving single short uses of this medicine have not shown a likely effect on behavior or learning. More research is needed.

In some cases, your doctor may decide to postpone a surgery based on these risks. Treatment may not be delayed in the case of life-threatening conditions, medical emergencies, or surgery needed to correct certain birth defects.

Ask your doctor for information about all medicines that will be used during your surgery, and how long the surgery will last.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

In an emergency, you may not be able to tell caregivers if you are pregnant or breastfeeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

How is Versed given?

Versed is injected into a muscle, or as an infusion into a vein. You will receive this injection in a medical, dental, or surgical setting.

Versed is usually given as a single dose just before a surgery or medical procedure. For mechanical ventilation, this medicine is given using a continuous infusion that keeps the patient sedated around the clock.

Versed can slow or stop your breathing, especially if you have recently used a narcotic (opioid) medication. This medicine should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.

Versed can make you very drowsy, dizzy, or light-headed. These effects may last longer in older adults. Use caution to avoid falling or accidental injury after you have received this medicine. You may need help getting out of bed for several hours.

After treatment with Versed, you will be watched to make sure the medication is working and does not cause harmful side effects. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely.

When Versed is discontinued after long-term use, you may have withdrawal symptoms. The most common withdrawal symptoms are hallucinations, tremors, sweating, muscle cramps, stomach pain, and vomiting. You may also have a seizure (convulsions).

What happens if I miss a dose?

Because you will receive Versed in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of midazolam can be fatal.

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving Versed?

Do not drink alcohol shortly after receiving Versed. Versed can increase the effects of alcohol, which could be dangerous.

Versed can cause extreme drowsiness that may last for several hours after you have received the medication. Older adults may feel sleepy for even longer.

Avoid driving or doing anything that requires you to be awake and alert until the effects of this medicine have worn off completely.

Versed side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • wheezing, trouble breathing, weak or shallow breathing;

  • slow heart rate;

  • a light-headed feeling, like you might pass out;

  • tremors, uncontrolled muscle movements; or

  • confusion, hallucinations, unusual thoughts or behavior.

The sedative effects of midazolam may last longer in older adults. Accidental falls are common in elderly patients who use benzodiazepines.

Common side effects may include:

  • headache;

  • drowsiness;

  • amnesia or forgetfulness after your procedure;

  • hiccups;

  • nausea, vomiting; or

  • pain, redness, or tenderness where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Versed?

Shortly after you are treated with Versed, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect Versed, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.