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Generic name: house dust mite allergen extract
Drug class: Allergenics

Medically reviewed by on May 13, 2024. Written by Cerner Multum.

What is Odactra?

Odactra contains allergen extract from common household dust mites. Dust mite allergies can trigger breathing problems or skin reactions.

Odactra is used to help your body develop an immunity to dust mites, and reduce symptoms such as sneezing, itching, and eye redness. This medicine is for use in adults up to age 65.

Odactra may also be used for purposes not listed in this medication guide.

Odactra side effects

Odactra may cause a severe allergic reaction. Stop taking the medicine and get emergency medical help if you have any of these signs of an allergic reaction:

If you stop taking Odactra after having an allergic reaction, do not start taking the medicine again without your doctor's advice.

Odactra may cause serious side effects. Call your doctor at once if you have:

Common side effects of Odactra may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


You should not use Odactra if you have uncontrolled asthma, or if you have a history of allergic reaction to an allergen or pollen extract medicine, or an allergic reaction that affected your esophagus.

You may not be able to use Odactra if you have breathing problems, heart disease, or high blood pressure, or if you use certain medicines.

Odactra may cause a severe allergic reaction. Your doctor will give you the first dose and watch you closely to make sure you do not have a reaction.

Before taking this medicine

You should not use Odactra if you've had an allergic reaction to similar allergen or pollen extract medicines, or if:

Tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take Odactra?

Your doctor may perform an allergy skin test or blood test to make sure you are allergic to the specific allergen contained in Odactra.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Your doctor will give you the first dose and watch you closely for at least 30 minutes, to make sure you do not have an allergic reaction.

Odactra is a sublingual tablet that dissolves under your tongue. Do not chew this tablet or swallow it whole.

To take the sublingual tablet:

Wash your hands after handling the sublingual tablet.

A child using Odactra should be supervised by an adult while taking this medicine.

Your doctor may also prescribe epinephrine (Epi-Pen) to keep with you in case you ever have an allergic reaction to Odactra.

If you need oral surgery or dental work, or if you have a mouth injury or infection, you may need to stop using this medicine until your mouth heals. Tell your doctor if the sublingual tablets cause any mouth irritation.

Store tablets in the blister pack at room temperature, away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Odactra?

Ask your doctor before starting any new medicine or treatments, including allergy shots.

What other drugs will affect Odactra?

Other drugs may affect Odactra, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Popular FAQ

With dry hands, remove the Odactra tablet from the foil blister pouch and then place the tablet under your tongue. The tablet dissolves within 10 seconds. Do not swallow for at least 1 minute.

Do not take Odactra with food or beverages, and avoid any food or beverages for at least 5 minutes after each dose. Your first dose is taken under the supervision of a health care provider due to the possibility of severe allergic reactions. Continue reading

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.