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Odactra Side Effects

Generic name: house dust mite allergen extract

Medically reviewed by Last updated on Aug 26, 2022.

Note: This document contains side effect information about house dust mite allergen extract. Some of the dosage forms listed on this page may not apply to the brand name Odactra.

Applies to house dust mite allergen extract: sublingual tablet

Other dosage forms:


Sublingual route (Tablet)

Dermatophagoides farinae and Dermatophagoides pteronyssinus extracts can cause life-threatening allergic reactions such as anaphylaxis and severe laryngopharyngeal restriction. Do not administer to patients with severe, unstable or uncontrolled asthma. Observe patients in the office for at least 30 minutes following the initial dose. Prescribe auto-injectable epinephrine, instruct and train patients on its appropriate use, and instruct patients to seek immediate medical care upon its use. Dermatophagoides farinae extract/Dermatophagoides pteronyssinus extract may not be suitable for patients with certain underlying medical conditions that may reduce their ability to survive a serious allergic reaction, as well as for those who may be unresponsive to epinephrine or inhaled bronchodilators, such as those taking beta-blockers.

Side effects requiring immediate medical attention

Along with its needed effects, house dust mite allergen extract (the active ingredient contained in Odactra) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking house dust mite allergen extract:

Incidence not known

  • Cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives, itching, or skin rash
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • sores or ulcers on the tongue
  • tightness in the chest
  • unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking house dust mite allergen extract:

Symptoms of overdose

  • Changes in voice
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

Side effects not requiring immediate medical attention

Some side effects of house dust mite allergen extract may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Change in taste
  • diarrhea
  • itching in the ear
  • itching or swelling in the mouth
  • nausea
  • stomach pain

Less common

  • Vomiting

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.