magnesium, potassium, and sodium sulfates
Generic Name: magnesium, potassium, and sodium sulfates (mag NEE see um, poe TAS ee um, SOE dee um SUL fates)
Brand Name: Suprep Bowel Prep Kit
What is magnesium, potassium, and sodium sulfates?
Magnesium, potassium, and sodium sulfates are used in a laxative that works by increasing the amount of water in your intestines and helps your bowels to move more quickly.
Magnesium, potassium, and sodium sulfates is a combination medicine used in adults to clean the bowel before a colonoscopy.
Magnesium, potassium, and sodium sulfates may also be used for purposes not listed in this medication guide.
What is the most important information I should know about magnesium, potassium, and sodium sulfates?
You should not take this medicine if you have a blockage in your stomach or intestines, slow digestion, colitis or toxic megacolon, or a perforated bowel.
What should I discuss with my healthcare provider before taking magnesium, potassium, and sodium sulfates?
You should not take this medicine if you are allergic to it, or if you have:
blockage in your digestive tract (stomach or intestines);
a perforated bowel; or
colitis or toxic megacolon.
This medicine causes loose stools or diarrhea, which can also result in fluid loss and electrolyte imbalances. This may be more likely if you have:
heart disease; or
if you take an NSAID (nonsteroidal anti-inflammatory drug).
To make sure this medicine is safe for you, tell your doctor if you have:
ulcerative colitis, inflammatory bowel disease;
trouble swallowing, gastroesophageal reflux disease (GERD);
heart disease, heart rhythm disorder, recent heart attack or heart surgery;
a seizure disorder;
recent withdrawal from drug or alcohol addiction; or
an electrolyte imbalance (such as high or low levels of potassium, sodium, phosphorous, or magnesium in your blood).
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Do not give this medicine to anyone under 5 years old without medical advice.
How should I take magnesium, potassium, and sodium sulfates?
Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. You may need to use 2 bottles to get your entire dose.
This medicine must be mixed (diluted) with water before you take it. Drinking the undiluted solution out of the medicine bottle can cause unpleasant or dangerous side effects.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
To keep from getting dehydrated, drink plenty of water or other clear liquids. Do not drink milk or any liquid colored red or purple. Follow your doctor's instructions about the type and amount of liquids to drink for 24 hours after taking magnesium, potassium, and sodium sulfates.
While taking this medicine, you must not eat any solid food. Drink only clear liquids.
Call your doctor if you are sick with vomiting, or if you are sweating more than usual. You may need blood tests to check your electrolyte levels.
Store at room temperature away from moisture and heat. Throw away any leftover medicine after your treatment ends.
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose or do not finish all doses required before your colonoscopy.
Do not use more than the recommended dose of this medicine in any 24-hour period.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking magnesium, potassium, and sodium sulfates?
Do not use any other laxatives at the same time.
This medicine can make it harder for your body to absorb other medicines you take by mouth. Avoid taking other oral medicines within 2 hours before or after you take magnesium, potassium, and sodium sulfates.
Magnesium, potassium, and sodium sulfates side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
headache, dizziness, vomiting, little or no urinating;
bloating, stomach cramps, trouble swallowing liquids;
fast, slow, or uneven heart rate;
fever, sudden or severe stomach pain, rectal bleeding or bright red bowel movements;
seizure (blackout or convulsions); or
no bowel movement after use.
Common side effects may include:
bloating or mild stomach discomfort.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Magnesium, potassium, and sodium sulfates dosing information
Usual Adult Dose for Bowel Preparation:
Magnesium/potassium/sodium sulfates bowel prep kit should be taken as a split-dose oral regimen.
The dose for colon cleansing requires administration of two bottles of magnesium/potassium/sodium sulfates bowel prep kit. Each bottle is administered as 16 ounces of diluted magnesium/potassium/sodium sulfates solution with an additional 1 quart of water taken orally. The total volume of liquid required for colon cleansing (using 2 bottles) is 3 quarts (approximately 2.8 L) taken orally prior to the colonoscopy in the following way:
Split-Dose (Two-Day) Regimen
Day prior to colonoscopy:
A light breakfast may be consumed, or have only clear liquids on the day before the colonoscopy. Nothing should be eaten for dinner. Avoid red and purple liquids, milk, and alcoholic beverages. Early in the evening prior to colonoscopy: pour the contents of 1 bottle of magnesium/potassium/sodium sulfates bowel prep kit into the mixing container provided. Fill the container with water to the 16 oz fill line, and drink the entire amount. Drink two additional containers filled to the 16 oz line with water over the next hour.
Day of colonoscopy:
Have only clear liquids until after the colonoscopy. Avoid red and purple liquids, milk, and alcoholic beverages. The morning of colonoscopy (10 to 12 hours after the evening dose): pour the contents of the second bottle of magnesium/potassium/sodium sulfates bowel prep into the mixing container provided. Fill the container with water to the 16 ounce fill line, and drink the entire amount. Drink two additional containers filled to the 16 oz line with water over the next hour.
Complete all magnesium/potassium/sodium sulfates bowel prep and required water at least two hours prior to colonoscopy.
What other drugs will affect magnesium, potassium, and sodium sulfates?
Tell your doctor about all your current medicines and any you start or stop using, especially:
heart or blood pressure medication;
medicine to treat kidney problems;
a diuretic or "water pill";
other laxatives; or
NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
This list is not complete. Other drugs may interact with magnesium, potassium, and sodium sulfates, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
See also: Side effects (in more detail)
More about magnesium sulfate/potassium sulfate/sodium sulfate
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 837 Reviews – Add your own review/rating
- Drug class: laxatives
- Sodium Sulfate, Potassium Sulfate, and Magnesium Sulfate
- Sodium sulfate, potassium sulfate, and magnesium sulfate (Advanced Reading)
Related treatment guides
Where can I get more information?
- Your doctor or pharmacist can provide more information about magnesium, potassium, and sodium sulfates.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 1.01.
Last reviewed: February 11, 2015
Date modified: September 05, 2017