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Magnesium sulfate / potassium sulfate / sodium sulfate Side Effects

Medically reviewed by Last updated on Jan 25, 2024.

Applies to magnesium sulfate / potassium sulfate / sodium sulfate: oral solution.

Serious side effects

Along with its needed effects, magnesium sulfate/potassium sulfate/sodium sulfate may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking magnesium sulfate / potassium sulfate / sodium sulfate:


Incidence not known

Other side effects

Some side effects of magnesium sulfate / potassium sulfate / sodium sulfate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to magnesium sulfate / potassium sulfate / sodium sulfate: oral liquid.


The most commonly reported side effects included overall discomfort, abdominal distention, abdominal pain, and nausea.[Ref]


Very common (10% or more): Abdominal distention (up to 40%), abdominal pain (up to 36%), nausea (up to 36%)

Common (1% to 10%): Abdominal bloating, vomiting

Frequency not reported: Colonic mucosal ulceration, ischemic colitis[Ref]


Very common (10% or more): Overall discomfort (up to 54%)[Ref]


Very common (10% or more): Low bicarbonate levels (up to 13%)

Common (1% to 10%): High calcium levels, high chloride levels, high osmolality, high uric acid

Frequency not reported: High potassium levels, serious electrolyte and fluid abnormalities[Ref]


Very common (10% or more): High blood urea nitrogen (BUN) (up to 11%)

Frequency not reported: High creatinine levels[Ref]


Common (1% to 10%):High total bilirubin[Ref]


Frequency not reported: Atrioventricular block, cardiac arrhythmias[Ref]

Nervous system

Frequency not reported: Seizures[Ref]


Frequency not reported: Aspiration[Ref]


Frequency not reported: CK increase[Ref]


1. Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates). Braintree Laboratories. 2010.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.