Generic name: magnesium sulfate, potassium sulfate, and sodium sulfate (mag NEE see um SUL fate, poe TA see um SUL fate, and SOE dee um SUL fate)
Brand name: Suprep Bowel Prep Kit
Drug class: Laxatives
Medically reviewed by Philip Thornton, DipPharm. Last updated on Sep 1, 2020.
What is Suprep Bowel Prep?
Suprep Bowel Prep contains a combination of magnesium, potassium, and sodium sulfates. Magnesium, potassium, and sodium are electrolyte minerals that occur naturally in body fluids and they are used in a laxative that works by increasing the amount of water in your intestines and helps your bowels to move more quickly.
Suprep is for use in adults and children at least 12 years old.
Before taking this medicine
You should not use Suprep if you are allergic to magnesium sulfate, potassium sulfate, or sodium sulfate, or if you have:
a dilated intestine;
a perforation (a hole or tear) of your intestines; or
To make sure Suprep is safe for you, tell your doctor if you have ever had:
heart problems, including long QT syndrome;
a stomach or intestinal disorder;
an electrolyte imbalance (such as low levels of potassium, magnesium, or sodium in your blood);
a sensitive gag reflex, or trouble swallowing;
alcohol or opioid withdrawal.
Tell your doctor if you are pregnant or breastfeeding.
Suprep Bowel Prep is not approved for use by anyone younger than 12 years old.
How should I take Suprep Bowel Prep?
Use the Suprep Bowel Prep exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Never use an adult-strength bowel prep kit in anyone 12 to 18 years old.
Carefully follow all instructions about what to eat or drink in the days before your colon prep.
You must dilute Suprep with water before drinking it. Drinking the pure liquid can increase your risk of nausea, vomiting, or dehydration.
Do not eat solid food once you start taking Suprep.
You will need to drink extra water once you start your colon prep. Drink only clear liquids and avoid alcohol, milk, or any drink that is red or purple.
Suprep can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure. Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.
Store at room temperature.
What happens if I miss a dose?
Call your doctor if you cannot drink the entire amount of medicine and liquids as instructed in time for your colonoscopy.
What happens if I overdose?
An overdose is unlikely to occur if you take Suprep Bowel Prep Kit exactly as directed.
What to avoid
Do not take other laxatives during your colon prep.
Suprep Bowel Prep side effects
Get emergency medical help if you have signs of an allergic reaction to Suprep: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor right away if you have:
a headache and dizziness;
little or no urination;
severe nausea or vomiting;
painful bloating or stomach cramps;
trouble drinking liquids;
irregular heartbeats; or
worsening gout symptoms (joint pain, redness, or swelling).
Common Suprep side effects may include:
stomach pain or discomfort;
nausea, vomiting; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Suprep Bowel Prep?
Suprep can make it harder for your body to absorb other medicines you take by mouth within 1 hour before your colon prep.
Tell your doctor about all your other medicines, especially:
heart or blood pressure medication;
a diuretic or "water pill";
medicine to treat a kidney problem;
seizure medication; or
This list is not complete. Other drugs may interact with sodium, potassium, and magnesium sulfates, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Frequently asked questions
More about Suprep Bowel Prep Kit (magnesium sulfate / potassium sulfate / sodium sulfate)
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- During Pregnancy
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- Drug class: laxatives
- FDA Approval History
- Other brands
- ColPrep Kit
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Suprep only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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