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Suprep Bowel Prep Kit

Generic Name: magnesium sulfate, potassium sulfate, and sodium sulfate (mag NEE see um SUL fate, poe TA see um SUL fate, and SOE dee um SUL fate)
Brand Names: Suprep Bowel Prep Kit

Medically reviewed by P. Thornton, DipPharm Last updated on Aug 1, 2019.

What is Suprep Bowel Prep Kit?

Suprep Bowel Prep Kit contains a combination of magnesium, potassium, and sodium sulfates. Magnesium, potassium, and sodium are electrolyte minerals that occur naturally in body fluids and they are used in a laxative that works by increasing the amount of water in your intestines and helps your bowels to move more quickly.

Suprep Bowel Prep Kit causes diarrhea for the purpose of cleaning your colon before a colonoscopy. Cleaning the colon allows the inside of your colon to be seen more clearly on the colonoscopy.

Suprep may also be used for purposes not listed in this medication guide.

Important Information

Suprep can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure.

Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

Before taking this medicine

You should not use Suprep if you are allergic to magnesium sulfate, potassium sulfate, or sodium sulfate, or if you have:

  • a bowel obstruction, colitis or toxic megacolon;

  • a dilated intestine;

  • a perforation (a hole or tear) of your intestines; or

  • slow digestion.

To make sure Suprep is safe for you, tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

How should I take Suprep Bowel Prep Kit?

Use the Suprep Bowel Prep Kit exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Carefully follow all instructions about what to eat or drink in the days before your colon prep.

You must dilute Suprep with water before drinking it. Drinking the pure liquid can increase your risk of nausea, vomiting, or dehydration.

Do not eat solid food once you start taking Suprep.

You will need to drink extra water once you start your colon prep. Drink only clear liquids and avoid alcohol, milk, or any drink that is red or purple.

Suprep can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure. Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

Store at room temperature.

What happens if I miss a dose?

Call your doctor if you cannot drink the entire amount of medicine and liquids as instructed in time for your colonoscopy.

What happens if I overdose?

An overdose is unlikely to occur if you take Suprep Bowel Prep Kit exactly as directed.

What should I avoid while taking Suprep?

Do not take other laxatives during your colon prep.

Suprep Bowel Prep Kit side effects

Get emergency medical help if you have signs of an allergic reaction to Suprep: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have:

  • a headache and dizziness;

  • little or no urination;

  • severe nausea or vomiting;

  • painful bloating or stomach cramps;

  • trouble drinking liquids;

  • mouth sores;

  • a seizure;

  • irregular heartbeats; or

  • worsening gout symptoms (joint pain, redness, or swelling).

Common Suprep side effects may include:

  • stomach pain or discomfort;

  • nausea, vomiting; or

  • mild bloating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Suprep Bowel Prep Kit?

Suprep can make it harder for your body to absorb other medicines you take by mouth within 1 hour before your colon prep.

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may interact with sodium, potassium, and magnesium sulfates, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Suprep only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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