Can you take Mavyret while pregnant?
It is not known if taking Mavyret will harm your unborn baby if you take it while pregnant. Patients are advised to tell their doctor if they are pregnant or plan to become pregnant before they start taking Mavyret.
Adequate information is not available from studies in humans to confirm whether or not Mavyret is safe in pregnancy, so it is not recommended for use in pregnant people. Mavyret has not been assigned to a US Food and Drug Administration (FDA) Pregnancy Category, which gives an indication of the expected safety of the drug during pregnancy.
Results from reproduction studies conducted in pregnant animals showed no adverse development effects when glecaprevir and pibrentasvir - the two active ingredients in Mavyret - were administered separately.
Mavyret contains a fixed dose of glecaprevir and pibrentasvir and is used to treat hepatitis C virus (HCV) infection genotypes 1 to 6 in people without cirrhosis or with compensated cirrhosis. It comes in the form of a tablet and oral pallets and is taken daily with food for 8-16 weeks.
References
- Food and Drug Administration (FDA). Mavyret. June 2021. [Accessed August 18, 20201]. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/215110s000,209394s013lbl.pdf.
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Drug information
- Mavyret Information for Consumers
- Mavyret prescribing info & package insert (for Health Professionals)
- Side Effects of Mavyret (detailed)
Related support groups
- Mavyret (25 questions, 48 members)