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Why take Mavyret with food?

Medically reviewed by Nicole France, BPharm. Last updated on Aug 17, 2021.

Official answer

by Drugs.com

Mavyret should be taken with food because it helps your body to absorb the medication better.

Mavyret is used for the treatment of hepatitis C virus (HCV) infection and contains a fixed dose of two drugs called glecaprevir and pibrentasvir. Mavyret is available as a tablet and oral pellets.

The mean systemic exposure to glecaprevir is increased 83-163 percent when Mavyret tablets are taken with food and 131-167 percent when Mavyret oral pellets are taken with food, compared with the mean systemic exposures seen when the drug is taken in a fasting state without a low/moderate to high fat meal.

The mean systemic exposure to pibrentasvir is increased 40-53 percent when Mavyret tablets are taken with food and 56-114 percent when Mavyret oral pellets are taken with food, compared with the mean systemic exposures seen when the drug is taken in a fasting state without a low/moderate to high fat meal.

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