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Why take Mavyret with food?

Medically reviewed by Philip Thornton, DipPharm. Last updated on Aug 7, 2024.

Official answer

by Drugs.com

Mavyret should be taken with food because it helps your body to absorb the medication better.

Mavyret is used for the treatment of hepatitis C virus (HCV) infection and contains a fixed dose of two drugs called glecaprevir and pibrentasvir. Mavyret is available as a tablet and oral pellets.

The mean systemic exposure to glecaprevir is increased 83-163 percent when Mavyret tablets are taken with food and 131-167 percent when Mavyret oral pellets are taken with food, compared with the mean systemic exposures seen when the drug is taken in a fasting state without a low/moderate to high fat meal.

The mean systemic exposure to pibrentasvir is increased 40-53 percent when Mavyret tablets are taken with food and 56-114 percent when Mavyret oral pellets are taken with food, compared with the mean systemic exposures seen when the drug is taken in a fasting state without a low/moderate to high fat meal.

References

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What is the difference between hepatitis B and C?

Some of the main differences between hepatitis B and C are:

  • Hepatitis B virus can be prevented with a vaccine, but not hepatitis C.
  • Hepatitis B and C are different viruses, but you can have both hepatitis B and hepatitis C at the same time.
  • Over 90% of people infected with hepatitis C who have not received treatment can be cured with 8 to 12 weeks of oral medications, but treatment for hepatitis B, if needed, may be long-term or lifelong.
  • There is no cure for hepatitis B, but once you recover from acute hepatitis B, you develop antibodies that protect you from the virus for life.
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What are the new drugs for the treatment of hepatitis C?

The newest drugs for the treatment of hepatitis C include Mavyret (glecaprevir and pibrentasvir), Vosevi (sofosbuvir, velpatasvir, and voxilaprevir), and Epclusa (sofosbuvir and velpatasvir). All are FDA-approved for the treatment of chronic hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis (Child-Pugh A), as well as other uses. Continue reading

How much does Mavyret cost?

The cost of Mavyret for 84 tablets is $13,909 if you are paying cash using an online discount card, however, most people do not pay this amount. If you are eligible, AbbVie offers a $5 per month Copay Savings Card. You can call 1-800-628-9738 to find out how much this medicine may cost you. Continue reading

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