What is the difference between Sympazan and Onfi?

Q: What is the difference between Sympazan and Onfi?

Sympazan (clobazam) is available an oral film that dissolves when placed on top of the tongue, and Onfi (clobazam) is available as an oral tablet or oral suspension. Clobazam belongs to the benzodiazepine class of drugs. Uses The Sympazan and Onfi brands of clobazam are prescription medicines used along with other medicines to treat seizures associated with Lennox-Gastaut syndrome in people 2 years of age or older. Dosage Forms Sympazan Onfi Oral Film : 5 mg, 10 mg and 20 mg Tablet : 10 mg and 20 mg Oral Suspension : 2.5 mg/mL Lennox-Gastaut syndrome (LGS) is a severe form of epilepsy that begins in early childhood and is characterized by multiple types of seizures and intellectual disability. LGS patients may often have difficulty swallowing pills and oral suspensions due to physical, behavioral or cognitive limitations. The Sympazan oral film may be an easier dosage form for LGS patients to use. The berry flavored Sympazan oral film is placed on top of the tongue where it dissolves without the need for liquid. Generic Availability Sympazan : There are no approved generic versions of Sympazan . Onfi : Generic versions of Onfi are available in both tablet and oral suspension dosage forms.

Medically reviewed by Judith Stewart, BPharm. Last updated on June 26, 2024.

Both drugs contain clobazam, so what is the difference between them?

Official answer

by Drugs.com

Sympazan (clobazam) is available an oral film that dissolves when placed on top of the tongue, and Onfi (clobazam) is available as an oral tablet or oral suspension.

Clobazam belongs to the benzodiazepine class of drugs.

Uses
The Sympazan and Onfi brands of clobazam are prescription medicines used along with other medicines to treat seizures associated with Lennox-Gastaut syndrome in people 2 years of age or older.

Dosage Forms

Sympazan	Onfi
Oral Film: 5 mg, 10 mg and 20 mg	Tablet: 10 mg and 20 mg Oral Suspension: 2.5 mg/mL

Lennox-Gastaut syndrome (LGS) is a severe form of epilepsy that begins in early childhood and is characterized by multiple types of seizures and intellectual disability.

LGS patients may often have difficulty swallowing pills and oral suspensions due to physical, behavioral or cognitive limitations. The Sympazan oral film may be an easier dosage form for LGS patients to use. The berry flavored Sympazan oral film is placed on top of the tongue where it dissolves without the need for liquid.

Generic Availability
Sympazan: There are no approved generic versions of Sympazan.
Onfi: Generic versions of Onfi are available in both tablet and oral suspension dosage forms.

What type of epilepsy is Diacomit used to treat?

Diacomit (stiripentol) is an oral anticonvulsant used with clobazam (Onfi) for seizures associated with Dravet syndrome in patients 6 months of age and older, weighing at least 7 kg (15.4 lbs), and taking the benzodiazepine clobazam (Onfi). Diacomit is not used alone to treat Dravet Syndrome, a rare, genetic form of epilepsy. It usually begins in infancy, often during a fever due to illness or vaccination. Continue reading

How long does it take for Lyrica to work?

In clinical studies with Lyrica, some patients experienced a decrease in pain as early as the first week, which persisted during the entire study period of 5 to 13 weeks. Continue reading

How long does Lyrica stay in your system?

Lyrica (pregabalin) will stay in your blood (plasma) for about 35 hours, but its clinical effect may wear off before this time. Studies have shown pregabalin to be detectable in urine for up to 5 to 6 days. Continue reading

Drug information

Related support groups

Onfi (5 questions, 12 members)
Clobazam (2 questions, 13 members)
Sympazan (1 questions, 3 members)
Epilepsy (92 questions, 408 members)
Lennox-Gastaut Syndrome (12 questions, 10 members)

Medical Disclaimer