What is the difference between Nexplanon and Implanon?

Medically reviewed by Drugs.com. Last updated on March 13, 2025.

Official Answer by Drugs.com

The brand name product Implanon is no longer commercially available in the U.S., and has been replaced by Nexplanon.

Nexplanon and Implanon are both long-acting, reversible hormonal contraceptive implants that contain etonogestrel, a hormone that prevents ovulation (the release of an egg from an ovary). Etonogestrel, a progestin hormone, leads to changes in the cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus. Etonogestrel is slowly released from a small plastic rod implanted in the skin of your upper arm.

Why is Nexplanon radiopaque? The Nexplanon implant is radiopaque because it contains a small amount of barium sulfate so that the implant can be seen by your doctor with an X-ray or other imaging tool. Being radiopaque is an advantage as physicians can verify presence of the implant after insertion. The rod can remain in place and provide continuous contraception for up to 3 years.

What are my birth control options and how effective are they?

Birth control refers to any behavioral, hormonal, spermicidal, or physical device that is used to prevent pregnancy. Unfortunately for most, human error ("Oops the condom broke", or "I forgot to take my pill") is the reason most forms of birth control (also called contraception) fail; and this has resulted in most manufacturers rating their product's effectiveness on a dual scale: perfect use (PU) and typical use (TU). Continue reading

What should I expect after a Mirena IUD removal?

It is typically less painful to get your Mirena IUD removed than it is to get it inserted but for a few hours or days after the removal you may experience some light pain and bleeding, cramping, or feel dizzy. An IUD removal typically takes about 5 minutes, but you should allow 20 minutes for the whole appointment. Consider eating something before your appointment so you are less likely to feel dizzy, and take some painkillers, such as acetaminophen or ibuprofen one hour before to help with any pain. Most women can go straight back to work or study or usual activities after the IUD is taken out. Continue reading

What are the signs that Plan B didn't work?

If you have had to take Plan B as an emergency contraceptive, you may be wondering if it has worked. While research shows it has an efficacy rate of 89% when used correctly, how easy is it to tell if it has worked for you? The easiest way to know that it hasn’t worked are a missed period and a positive pregnancy test. Continue reading

What is the difference between Nexplanon and Implanon?

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What are my birth control options and how effective are they?

What should I expect after a Mirena IUD removal?

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