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Opill OTC vs other birth control pills: What's the difference?

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 22, 2023.

Official answer

by Drugs.com

Opill is a progestin-only pill, which makes it different from other birth control pills that contain both estrogen and a progestin (such as Yaz, Junel FE, Lutera, or Sprintec) although you can get progestin-only pills (such as Cerazette, errin, and Heather) on prescription. Progestin-only pills are often called mini-pills, so Opill is a type of mini-pill.

Is Opill as effective as other birth control?

Progestin-only pills, including Opill, may have a slightly lower effectiveness compared to combination estrogen/progestin pills. To enhance their efficacy, it is recommended to take them consistently at the same time each day or within a 3-hour window of the same time daily. Progestin-only pills are often chosen for birth control by individuals who cannot take estrogen, including those who are breastfeeding.

How does Opill work?

Opill prevents conception in several different ways:

  • Thickening cervical mucus to inhibit sperm penetration
  • Lowering the midcycle LH and FSH peaks
  • Slowing the movement of the egg through the fallopian tubes
  • Altering the lining of the endometrium
  • Suppressing ovulation in approximately half of the menstrual cycles of females who use it.
References
  • Opill Tablets https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017031s035s036lbl.pdf

Read next

How do I use Opill birth control?

Take one Opill tablet at the same time every day, with or without food. Choose a good time for you to take it each day. It's important you take your Opill at the same time every day (and no later than 3 hours from your normal time). If you take a pill late, and especially if you miss a pill, you are more likely to get pregnant. Continue reading

How much does Opill cost?

Opill costs $19.99 for a 1-month pack (28 pills), $49.99 for a 3-month pack (84 pills) and $89.99 for a 6-month pack (168 pills) when purchased online on the Opill website. Shipping is free and packaging is discreet. You can save 5% with auto-shipping. Retail prices in stores may vary. Continue reading

How effective is Opill OTC birth control?

Opill is 93% effective at preventing pregnancy with typical use and 98% effective when used perfectly. As with any birth control method, Opill does not prevent pregnancy all of the time. Opill is NOT for use as an emergency contraceptive and will not prevent pregnancy after unprotected sex. Continue reading

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