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In the US, Trabectedin (trabectedin systemic) is a member of the drug class alkylating agents and is used to treat Soft Tissue Sarcoma.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Antineoplastic agent

Chemical Name

(1'R,6R,6aR,7R,13S,14S,16R)-6',8,14-Trihydroxy-7',9-dimetoxy-4,10,23-trimetyl-19-oxo-3',4',6,7,12,13,14,16-octahydrospiro[6,16-(epitiopropanooxymetano)-7,13-imino-6aH-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20-1'(2'H)-isoquinolin]-5-yl acetate (WHO)

Foreign Names

  • Trabectedinum (Latin)
  • Trabectedin (German)
  • Trabect├ędine (French)
  • Trabectedina (Spanish)

Generic Names

  • Trabectedin (OS: USAN, BAN, JAN)
  • Ecteinascidin 743 (IS)
  • ET 743 (PharmaMar) (IS)
  • ET-722 (IS)
  • ET-729 (IS)
  • ET-736 (IS)
  • ET-745 (IS)
  • ET-759A (IS)
  • ET-759B (IS)
  • ET-770 (IS)
  • NSC-648766 (IS)

Brand Names

  • Yondelis
    Janssen, Canada; Janssen, Chile; Janssen, Malaysia; Janssen, Singapore; Janssen, South Africa; Janssen Cilag, Argentina; Janssen Pharma, United States; Janssen-Cilag, Colombia; Janssen-Cilag, Mexico; Janssen-Cilag, Oman; Janssen-Cilag, Uruguay; Johnson & Johnson, Hong Kong; Johnson & Johnson, Turkey; Medical Intertrade, Croatia (Hrvatska); Pharma Mar, Belgium; Pharma Mar, Cyprus; Pharma Mar, Czech Republic; Pharma Mar, Spain; Pharma Mar, France; Pharma Mar, United Kingdom; Pharma Mar, Ireland; Pharma Mar, Iceland; Pharma Mar, Italy; Pharma Mar, Lithuania; Pharma Mar, Latvia; Pharma Mar, Norway; Pharma Mar, Poland; Pharma Mar, Romania; Pharma Mar, Slovenia; Pharma Mar S.A., Netherlands; Pharma Mar,, Estonia; Pharmamar SA, Greece; SOBI, Sweden; Swedish Orphan Biovitrum, Denmark; Swedish Orphan Biovitrum, Finland; Taiho Yakuhin, Japan
  • Yondelis 0,25mg
    Pharma Mar, Austria; Pharma Mar, Germany; Pharma Mar, Luxembourg; PharmaMar, Switzerland
  • Yondelis 0.25 mg
    Pharma Mar, Hungary
  • Yondelis 1 mg
    Pharma Mar, Hungary
  • Yondelis 1mg
    J-C Healthcare, Israel; Pharma Mar, Austria; Pharma Mar, Germany; Pharma Mar, Luxembourg; PharmaMar, Switzerland


BANBritish Approved Name
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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