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Trabectedin

In the US, Trabectedin (trabectedin systemic) is a member of the drug class alkylating agents and is used to treat Soft Tissue Sarcoma.

US matches:

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01CX01

CAS registry number (Chemical Abstracts Service)

0114899-77-3

Chemical Formula

C39-H43-N33-O11-S

Molecular Weight

762

Therapeutic Category

Antineoplastic agent

Chemical Name

(1'R,6R,6aR,7R,13S,14S,16R)-6',8,14-Trihydroxy-7',9-dimetoxy-4,10,23-trimetyl-19-oxo-3',4',6,7,12,13,14,16-octahydrospiro[6,16-(epitiopropanooxymetano)-7,13-imino-6aH-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20-1'(2'H)-isoquinolin]-5-yl acetate (WHO)

Foreign Names

  • Trabectedinum (Latin)
  • Trabectedin (German)
  • Trabect├ędine (French)
  • Trabectedina (Spanish)

Generic Names

  • Trabectedin (OS: USAN, BAN, JAN)
  • Ecteinascidin 743 (IS)
  • ET 743 (PharmaMar) (IS)
  • ET-722 (IS)
  • ET-729 (IS)
  • ET-736 (IS)
  • ET-745 (IS)
  • ET-759A (IS)
  • ET-759B (IS)
  • ET-770 (IS)
  • NSC-648766 (IS)

Brand Names

  • Yondelis
    Janssen, Canada; Janssen, Chile; Janssen, Malaysia; Janssen, Singapore; Janssen, South Africa; Janssen Cilag, Argentina; Janssen Pharma, United States; Janssen-Cilag, Colombia; Janssen-Cilag, Mexico; Janssen-Cilag, Oman; Janssen-Cilag, Uruguay; Johnson & Johnson, Hong Kong; Johnson & Johnson, Turkey; Medical Intertrade, Croatia (Hrvatska); Pharma Mar, Belgium; Pharma Mar, Cyprus; Pharma Mar, Czech Republic; Pharma Mar, Spain; Pharma Mar, France; Pharma Mar, United Kingdom; Pharma Mar, Ireland; Pharma Mar, Iceland; Pharma Mar, Italy; Pharma Mar, Lithuania; Pharma Mar, Latvia; Pharma Mar, Norway; Pharma Mar, Poland; Pharma Mar, Romania; Pharma Mar, Slovenia; Pharma Mar S.A., Netherlands; Pharma Mar,, Estonia; Pharmamar SA, Greece; SOBI, Sweden; Swedish Orphan Biovitrum, Denmark; Swedish Orphan Biovitrum, Finland; Taiho Yakuhin, Japan
  • Yondelis 0,25mg
    Pharma Mar, Austria; Pharma Mar, Germany; Pharma Mar, Luxembourg; PharmaMar, Switzerland
  • Yondelis 0.25 mg
    Pharma Mar, Hungary
  • Yondelis 1 mg
    Pharma Mar, Hungary
  • Yondelis 1mg
    J-C Healthcare, Israel; Pharma Mar, Austria; Pharma Mar, Germany; Pharma Mar, Luxembourg; PharmaMar, Switzerland

Glossary

TermDefinition
BANBritish Approved Name
ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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