Ibuprofen Interactions
There are 415 drugs known to interact with ibuprofen, along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 99 are major, 301 are moderate, and 15 are minor.
- View all 415 medications that may interact with ibuprofen
- View ibuprofen alcohol/food interactions (2)
- View ibuprofen disease interactions (11)
Most frequently checked interactions
View interaction reports for ibuprofen and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Aleve (naproxen)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flexeril (cyclobenzaprine)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Norco (acetaminophen / hydrocodone)
- Paracetamol (acetaminophen)
- ProAir HFA (albuterol)
- Prozac (fluoxetine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zofran (ondansetron)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Ibuprofen alcohol/food interactions
There are 2 alcohol/food interactions with ibuprofen.
Ibuprofen disease interactions
There are 11 disease interactions with ibuprofen which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- PKU
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
Report options
More about ibuprofen
- ibuprofen consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (240)
- Drug images
- Latest FDA alerts (14)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: Nonsteroidal anti-inflammatory drugs
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Qulipta
Qulipta is used to help prevent episodic or chronic migraine headaches in adults. Qulipta is an ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Diclofenac
Diclofenac is a nonsteroidal anti-inflammatory drug used to treat pain and inflammation associated ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Amitriptyline
Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
