Midazolam and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with midazolam.
Midazolam Food/Lifestyle
Moderate Food Interaction
Grapefruit and grapefruit juice may interact with midazolam and lead to potentially dangerous side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Do not drink alcohol while taking midazolam. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you take midazolam with alcohol. Talk to your doctor or pharmacist if you have any questions or concerns.
Switch to professional interaction data
Midazolam Obesity
Moderate Potential Hazard, High plausibility
benzodiazepines - obesity
The plasma half-lives of benzodiazepines may be prolonged in obese patients, presumably due to increased distribution into fat. Marked increases in distribution (> 100%) have been reported for diazepam and midazolam, and moderate increases (25% to 100%) for alprazolam, lorazepam, and oxazepam. Therapy with benzodiazepines should be administered cautiously in obese patients, with careful monitoring of CNS status. Longer dosing intervals may be appropriate. When dosing by weight, loading doses should be based on actual body weight, while maintenance dose should be based on ideal body weight to avoid toxicity.
Switch to professional interaction data
Midazolam drug interactions
There are 578 drug interactions with midazolam.
Midazolam disease interactions
There are 12 disease interactions with midazolam which include:
- acute alcohol intoxication
- closed-angle glaucoma
- respiratory depression
- seizures
- prolonged hypotension
- prematurity
- CNS depression/electrolyte disturbances
- congestive heart failure
- renal/liver disease
- depression
- obesity
- paradoxical reactions
More about midazolam
- midazolam consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (147)
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: benzodiazepines
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Ativan
Ativan is a benzodiazepine used to treat anxiety disorders or anxiety associated with depression ...
Valium
Valium is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Learn ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Haldol
Haldol is used for dementia, ICU Agitation, mania, nausea/vomiting, psychosis, tourette's syndrome
Versed
Versed is used for ICU Agitation, light anesthesia, light sedation
Nayzilam
Nayzilam (midazolam) is used to treat seizure clusters. Information includes Nayzilam side effects ...
Valtoco
Valtoco nasal spray is used for the acute treatment of intermittent seizure clusters (also known as ...
Haldol Decanoate
Haldol Decanoate is used for dementia, ICU Agitation, mania, nausea/vomiting, psychosis, tourette's ...
Haloperidol
Haloperidol is used for aggressive behavior, borderline personality disorder, dementia, ICU ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.