Darifenacin and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with darifenacin.
Darifenacin Food
Minor Food Interaction
The consumption of grapefruit juice may be associated with increased plasma concentrations of darifenacin. The mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. The clinical significance is unknown.
References (1)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
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Darifenacin drug interactions
There are 426 drug interactions with darifenacin.
Darifenacin disease interactions
There are 5 disease interactions with darifenacin which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
