Zanaflex Drug Interactions
Currently displaying a list of 652 drugs known to interact with Zanaflex (tizanidine).
- 249 major drug interactions
- 401 moderate drug interactions
- 2 minor drug interactions
Medications known to interact with Zanaflex
Note: Showing generic names only.
A
- abametapir topical
- abarelix
- abiraterone
- abobotulinumtoxinA
- acebutolol
- acetazolamide
- acetylcarbromal
- acrivastine
- acyclovir
- adagrasib
- adalimumab
- adenosine
- albuterol
- aldesleukin
- alefacept
- alfentanil
- alfuzosin
- aliskiren
- allopurinol
- almotriptan
- alprazolam
- ambrisentan
- amiloride
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amyl nitrite
- anagrelide
- anakinra
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprocitentan
- arformoterol
- aripiprazole
- arsenic trioxide
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atenolol
- atomoxetine
- atropine
- azatadine
- azelastine nasal
- azilsartan medoxomil
- azithromycin
B
- baclofen
- bedaquiline
- belladonna
- benazepril
- bendroflumethiazide
- benzgalantamine
- benzonatate
- benzthiazide
- benztropine
- bepridil
- betaxolol
- bicalutamide
- bimekizumab
- biperiden
- bisoprolol
- bitolterol
- black cohosh
- bosentan
- brentuximab
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- brodalumab
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabergoline
- cabozantinib
- caffeine
- calaspargase pegol
- canakinumab
- candesartan
- cannabidiol
- cannabis
- capmatinib
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carvedilol
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- cilostazol
- cimetidine
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clemastine
- clevidipine
- clobazam
- clofarabine
- clofazimine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- conjugated estrogens
- conjugated estrogens topical
- crizotinib
- cyclandelate
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- daclizumab
- dantrolene
- daridorexant
- darolutamide
- dasatinib
- daunorubicin
- daunorubicin liposomal
- daxibotulinumtoxinA
- deferasirox
- degarelix
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- diazoxide
- dichlorphenamide
- dicyclomine
- difelikefalin
- diltiazem
- dimenhydrinate
- diphenhydramine
- disopyramide
- disulfiram
- divalproex sodium
- dofetilide
- dolasetron
- donepezil
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- duloxetine
E
- echinacea
- efavirenz
- eletriptan
- elranatamab
- emapalumab
- enalapril
- enalaprilat
- encorafenib
- enoxacin
- entacapone
- entrectinib
- enzalutamide
- epcoritamab
- epirubicin
- eplerenone
- epoprostenol
- eprosartan
- eribulin
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- estradiol
- estradiol topical
- eszopiclone
- ethacrynic acid
- ethanol
- ethaverine
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etonogestrel
- etranacogene dezaparvovec
- etrasimod
- ezogabine
F
- famotidine
- felbamate
- felodipine
- fenoldopam
- fentanyl
- fexinidazole
- fidanacogene elaparvovec
- fingolimod
- flavoxate
- flecainide
- flibanserin
- fluconazole
- fluoxetine
- fluphenazine
- flurazepam
- flutamide
- fluvoxamine
- formoterol
- foscarnet
- fosinopril
- fosphenytoin
- fospropofol
- fostemsavir
- frovatriptan
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- givinostat
- givosiran
- glasdegib
- glofitamab
- golimumab
- goserelin
- granisetron
- grepafloxacin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
- guselkumab
H
- halazepam
- halofantrine
- haloperidol
- halothane
- heroin
- histrelin
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
- hyoscyamine
I
- ibutilide
- idarubicin
- idelalisib
- ifosfamide
- iloperidone
- iloprost
- imipramine
- inamrinone
- incobotulinumtoxinA
- indacaterol
- indapamide
- infliximab
- inotuzumab ozogamicin
- interferon alfa-2b
- interferon beta-1a
- interferon beta-1b
- irbesartan
- isocarboxazid
- isoetharine
- isoniazid
- isoproterenol
- isosorbide
- isosorbide dinitrate
- isosorbide mononitrate
- isoxsuprine
- isradipine
- ivabradine
- ivosidenib
K
L
- labetalol
- lacosamide
- lamotrigine
- landiolol
- lapatinib
- lasmiditan
- lefamulin
- leflunomide
- lemborexant
- leniolisib
- lenvatinib
- letibotulinumtoxinA
- leuprolide
- levalbuterol
- levamlodipine
- levetiracetam
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- levorphanol
- lisdexamfetamine
- lisinopril
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- loperamide
- lorazepam
- losartan
- loxapine
- lumateperone
- lurasidone
M
- macimorelin
- macitentan
- maprotiline
- maraviroc
- mavorixafor
- mecamylamine
- meclizine
- medroxyprogesterone
- mefloquine
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaproterenol
- metaxalone
- methadone
- methazolamide
- methdilazine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methoxsalen
- methsuximide
- methyclothiazide
- methyldopa
- metoclopramide
- metolazone
- metoprolol
- metronidazole
- metyrosine
- mexiletine
- mibefradil
- midazolam
- midostaurin
- mifepristone
- milrinone
- minoxidil
- mipomersen
- mirtazapine
- mitotane
- mobocertinib
- moexipril
- molindone
- morphine
- morphine liposomal
- mosunetuzumab
- moxifloxacin
N
- nabilone
- nadolol
- nalbuphine
- nalidixic acid
- naltrexone
- naratriptan
- nebivolol
- nefazodone
- nemolizumab
- nesiritide
- nicardipine
- niclosamide
- nicotine
- nifedipine
- nilotinib
- nilutamide
- nimodipine
- niraparib
- nisoldipine
- nitroglycerin
- nitroprusside
- norethindrone
- norfloxacin
- norgestrel
- nortriptyline
O
- obeticholic acid
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olmesartan
- olodaterol
- olopatadine nasal
- onabotulinumtoxinA
- ondansetron
- opicapone
- opium
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- oxytocin
- ozanimod
P
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- pasireotide
- pazopanib
- pegaspargase
- peginterferon alfa-2a
- peginterferon alfa-2b
- peginterferon beta-1a
- penbutolol
- pentamidine
- pentazocine
- pentobarbital
- perampanel
- perflutren
- pergolide
- perindopril
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phenoxybenzamine
- phensuximide
- phentolamine
- phenytoin
- pimavanserin
- pimozide
- pindolol
- pirbuterol
- pitolisant
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponesimod
- posaconazole
- prabotulinumtoxinA
- pralsetinib
- pramipexole
- prazosin
- pregabalin
- primaquine
- primidone
- probucol
- procainamide
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propafenone
- propiomazine
- propofol
- propoxyphene
- propranolol
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ramipril
- ranolazine
- rauwolfia serpentina
- relugolix
- remdesivir
- remifentanil
- remimazolam
- reserpine
- revumenib
- ribociclib
- rifampin
- rilonacept
- rilpivirine
- rimabotulinumtoxinB
- risperidone
- ritlecitinib
- ritodrine
- rivastigmine
- rizatriptan
- rofecoxib
- romidepsin
- ropinirole
- rotigotine
- rucaparib
- rufinamide
S
- salmeterol
- saquinavir
- sarilumab
- satralizumab
- scopolamine
- scopolamine ophthalmic
- secobarbital
- secukinumab
- selpercatinib
- sertraline
- sevoflurane
- sibutramine
- siltuximab
- siponimod
- sodium oxybate
- solifenacin
- sorafenib
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sulfamethoxazole
- sumatriptan
- sunitinib
- suvorexant
T
- tacrine
- tacrolimus
- talquetamab
- tamoxifen
- tamsulosin
- tapentadol
- tarlatamab
- tasimelteon
- tebentafusp
- teclistamab
- telavancin
- telithromycin
- telmisartan
- temazepam
- terazosin
- terbutaline
- terfenadine
- teriflunomide
- tetrabenazine
- thalidomide
- thiabendazole
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- ticlopidine
- timolol
- tocilizumab
- tolazoline
- tolcapone
- tolterodine
- topiramate
- toremifene
- torsemide
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treprostinil
- triamterene
- triazolam
- trichlormethiazide
- triclabendazole
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- triptorelin
- tryptophan
U
V
- valbenazine
- valerian
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vandetanib
- vardenafil
- varenicline
- vasopressin
- vemurafenib
- venlafaxine
- verapamil
- vigabatrin
- viloxazine
- voclosporin
- voriconazole
Z
Zanaflex alcohol/food interactions
There are 3 alcohol/food interactions with Zanaflex (tizanidine).
Zanaflex disease interactions
There are 4 disease interactions with Zanaflex (tizanidine) which include:
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More about Zanaflex (tizanidine)
- Zanaflex consumer information
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- Drug class: skeletal muscle relaxants
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
