Zanaflex (tizanidine) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Zanaflex (tizanidine) which include:
Caffeine ↔ tiZANidine
Major Drug Interaction
Using tiZANidine together with caffeine is generally not recommended. Combining these medications may significantly increase the blood levels and effects of tiZANidine. This may cause blood pressure to fall excessively, especially when you rise from a sitting or lying position. The risk of other side effects such as drowsiness, dizziness, lightheadedness, and fainting may also increase. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Alcohol (Ethanol) ↔ tiZANidine
Moderate Drug Interaction
Using tiZANidine together with ethanol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Zanaflex (tizanidine) drug Interactions
There are 977 drug interactions with Zanaflex (tizanidine)
Zanaflex (tizanidine) disease Interactions
There are 4 disease interactions with Zanaflex (tizanidine) which include:
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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