Sorafenib Drug Interactions
Currently displaying a list of 430 drugs known to interact with sorafenib.
- 88 major drug interactions
- 334 moderate drug interactions
- 8 minor drug interactions
Medications known to interact with sorafenib
Note: Showing generic names only.
A
- abametapir topical
- abarelix
- abiraterone
- adagrasib
- adenosine
- afatinib
- albuterol
- alfuzosin
- aliskiren
- ambrisentan
- aminoglutethimide
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- anagrelide
- anisindione
- apalutamide
- apixaban
- apomorphine
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- artesunate
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atomoxetine
- azithromycin
B
- bedaquiline
- belinostat
- belzutifan
- benzgalantamine
- bepridil
- berotralstat
- betrixaban
- bexarotene
- bicalutamide
- binimetinib
- bisacodyl
- bitolterol
- black cohosh
- bosentan
- bosutinib
- brentuximab
- brigatinib
- buprenorphine
- butabarbital
- butalbital
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- cannabidiol
- capecitabine
- carbamazepine
- carboplatin
- casanthranol
- cascara sagrada
- castor oil
- cenobamate
- ceritinib
- chloroquine
- chlorpromazine
- cholic acid
- cilostazol
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clofarabine
- clofazimine
- clomipramine
- clozapine
- colchicine
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclizumab
- dapagliflozin
- daprodustat
- daridorexant
- darolutamide
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deferiprone
- degarelix
- desipramine
- deutetrabenazine
- dexamethasone
- dicumarol
- digoxin
- disopyramide
- docetaxel
- dofetilide
- dolasetron
- dolutegravir
- donepezil
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
E
- echinacea
- edoxaban
- efavirenz
- elafibranor
- elagolix
- encorafenib
- entrectinib
- enzalutamide
- epirubicin
- eribulin
- erlotinib
- erythromycin
- escitalopram
- eslicarbazepine
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- everolimus
- ezogabine
F
- famotidine
- felbamate
- fenfluramine
- fexinidazole
- fexofenadine
- fidanacogene elaparvovec
- fidaxomicin
- fingolimod
- flecainide
- fluconazole
- fluorouracil
- fluoxetine
- fluphenazine
- flutamide
- formoterol
- foscarnet
- fosphenytoin
- fostamatinib
- fostemsavir
G
- galantamine
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glycerin
- glycerol phenylbutyrate
- goserelin
- granisetron
- grepafloxacin
- griseofulvin
H
I
- ibutilide
- idarubicin
- idelalisib
- iloperidone
- imipramine
- indacaterol
- inotuzumab ozogamicin
- interferon beta-1a
- interferon beta-1b
- iptacopan
- irinotecan
- irinotecan liposomal
- isoetharine
- isoniazid
- isoproterenol
- ivabradine
- ivosidenib
K
L
- lactitol
- lactulose
- lapatinib
- larotrectinib
- lefamulin
- leflunomide
- lemborexant
- lenalidomide
- lenvatinib
- lesinurad
- leuprolide
- levalbuterol
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levothyroxine
- levothyroxine / liothyronine
- liothyronine
- liotrix
- lisdexamfetamine
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lonapegsomatropin
- loperamide
- lorlatinib
- lumateperone
- lusutrombopag
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- maraviroc
- mavacamten
- mavorixafor
- mefloquine
- mephobarbital
- mesoridazine
- metaproterenol
- methadone
- methotrexate
- methotrimeprazine
- metreleptin
- metronidazole
- mibefradil
- midostaurin
- mifepristone
- mineral oil
- mipomersen
- mirtazapine
- mitapivat
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- morphine
- moxifloxacin
N
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- neomycin
- nevirapine
- nilotinib
- nilutamide
- nintedanib
- norfloxacin
- nortriptyline
O
- obeticholic acid
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olutasidenib
- omacetaxine
- omaveloxolone
- ondansetron
- oritavancin
- osilodrostat
- osimertinib
- ospemifene
- oxaliplatin
- oxcarbazepine
- oxytocin
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- pasireotide
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pentamidine
- pentobarbital
- perflutren
- perphenazine
- pexidartinib
- phenobarbital
- phenolphthalein
- phenylbutazone
- phenytoin
- pimavanserin
- pimozide
- pirbuterol
- pirtobrutinib
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- ponesimod
- posaconazole
- pralsetinib
- pretomanid
- primaquine
- primidone
- probucol
- procainamide
- prochlorperazine
- promazine
- promethazine
- propafenone
- propofol
- propoxyphene
- protriptyline
Q
R
- raltegravir
- ranolazine
- relugolix
- remdesivir
- repotrectinib
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rifaximin
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritodrine
- rivaroxaban
- rivastigmine
- romidepsin
- romosozumab
- ropeginterferon alfa-2b
- rucaparib
- rufinamide
S
- sacituzumab govitecan
- salmeterol
- saquinavir
- secobarbital
- selpercatinib
- senna
- sertraline
- sevoflurane
- silodosin
- siponimod
- sirolimus
- sodium phenylbutyrate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotalol
- sotorasib
- sparfloxacin
- st. john's wort
- stiripentol
- sulfamethoxazole
- sulfinpyrazone
- sunitinib
- suzetrigine
T
- tacrine
- tacrolimus
- talazoparib
- tamoxifen
- tazemetostat
- tebentafusp
- tecovirimat
- telavancin
- telithromycin
- telotristat
- terbutaline
- terfenadine
- teriflunomide
- tetrabenazine
- thalidomide
- thioguanine
- thioridazine
- thyroid desiccated
- ticagrelor
- tipranavir
- tizanidine
- tolvaptan
- topotecan
- toremifene
- tovorafenib
- trabectedin
- tramadol
- trazodone
- treprostinil
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimipramine
- triptorelin
- trofinetide
- troglitazone
- tucatinib
U
V
- vadadustat
- valbenazine
- valoctocogene roxaparvovec
- vamorolone
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- venetoclax
- venlafaxine
- vibegron
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vismodegib
- voclosporin
- vorasidenib
- voriconazole
W
Z
Sorafenib alcohol/food interactions
There is 1 alcohol/food interaction with sorafenib.
Sorafenib disease interactions
There is 1 disease interaction with sorafenib which include:
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More about sorafenib
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- Drug class: multikinase inhibitors
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
